Detection of Endogenous Matrix Metalloprotease-12 Active Form with a Novel Broad Spectrum Activity-based Probe

How Chemoproteomics Can Enable Drug Discovery and Development

(2012) Raymond E. Moellering et al.   CHEMISTRY & BIOLOGY

Quantification of matrix metalloprotease-9 in bronchoalveolar lavage fluid by selected reaction monitoring with microfluidics nano-liquid-chromatography–mass spectrometry

(2012) Laurette M. Prely et al.   JOURNAL OF CHROMATOGRAPHY A

New approaches for dissecting protease functions to improve probe development and drug discovery

(2012) Edgar Deu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Selective Matrix Metalloproteinase-12 Inhibitor Retards Atherosclerotic Plaque Development in Apolipoprotein E–Knockout Mice

(2011) Jason L. Johnson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Elastases from inflammatory and dendritic cells mediate ultrafine carbon black induced acute lung destruction in mice

(2011) Chih-Ching Chang et al.   INHALATION TOXICOLOGY

An immunoaffinity liquid chromatography–tandem mass spectrometry assay for the quantitation of matrix metalloproteinase 9 in mouse serum

(2010) Mireia Fernández Ocaña et al.   ANALYTICAL BIOCHEMISTRY

Activity-Based Profiling Reveals Reactivity of the Murine Thymoproteasome-Specific Subunit β5t

(2010) Bogdan I. Florea et al.   CHEMISTRY & BIOLOGY

Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study

(2010) Gabriel M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum

(2010) Peter LaPan et al.   BMC Pulmonary Medicine

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Covalent Modification of Matrix Metalloproteinases by a Photoaffinity Probe: Influence of Nucleophilicity and Flexibility of the Residue in Position 241

(2009) Anne-Sophie Dabert-Gay et al.   BIOCONJUGATE CHEMISTRY

Matrix metalloproteinase proteomics: substrates, targets, and therapy

(2009) Charlotte J Morrison et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphinic Tripeptides as Dual Angiotensin-Converting Enzyme C-Domain and Endothelin-Converting Enzyme-1 Inhibitors

(2009) Nicolas Jullien et al.   JOURNAL OF MEDICINAL CHEMISTRY

Detection of Matrix Metalloproteinase Active Forms in Complex Proteomes: Evaluation of Affinity versus Photoaffinity Capture

(2009) Sarah Bregant et al.   JOURNAL OF PROTEOME RESEARCH

Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation

(2009) Amanda Cobos-Correa et al.   Nature Chemical Biology

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

(2009) Dale W. Porter et al.   TOXICOLOGY

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

(2008) Benjamin F. Cravatt et al.   Annual Review of Biochemistry

Molecular Determinants of Matrix Metalloproteinase-12 Covalent Modification by a Photoaffinity Probe

(2008) Anne-Sophie Dabert-Gay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic active site-directed inhibitors of metzincins: Achievement and perspectives

(2008) A YIOTAKIS et al.   MOLECULAR ASPECTS OF MEDICINE

An integrated high-performance liquid chromatography–mass spectrometry system for the activity-dependent analysis of matrix metalloproteases

(2007) Robert Freije et al.   JOURNAL OF CHROMATOGRAPHY A