Phosphorylation of Adaptor Protein Containing Pleckstrin Homology Domain, Phosphotyrosine Binding Domain, and Leucine Zipper Motif 1 (APPL1) at Ser430Mediates Endoplasmic Reticulum (ER) Stress-induced Insulin Resistance in Hepatocytes

APPL1 Mediates Adiponectin-Induced LKB1 Cytosolic Localization Through the PP2A-PKCζ Signaling Pathway

(2011) Sathyaseelan S. Deepa et al.   MOLECULAR ENDOCRINOLOGY

APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway

(2010) Xiaoban Xin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

DsbA-L Alleviates Endoplasmic Reticulum Stress-Induced Adiponectin Downregulation

(2010) L. Zhou et al.   DIABETES

Adiponectin receptor binding proteins - recent advances in elucidating adiponectin signalling pathways

(2010) Christa Buechler et al.   FEBS LETTERS

Identification of Phosphorylation Sites within the Signaling Adaptor APPL1 by Mass Spectrometry

(2010) Randi L. Gant-Branum et al.   JOURNAL OF PROTEOME RESEARCH

APPL1 Potentiates Insulin-Mediated Inhibition of Hepatic Glucose Production and Alleviates Diabetes via Akt Activation in Mice

(2009) Kenneth K.Y. Cheng et al.   Cell Metabolism

Adiponectin Activates AMP-activated Protein Kinase in Muscle Cells via APPL1/LKB1-dependent and Phospholipase C/Ca2+/Ca2+/Calmodulin-dependent Protein Kinase Kinase-dependent Pathways

(2009) Lijun Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Adiponectin Receptors AdipoR1 and AdipoR2 Activate ERK1/2 through a Src/Ras-Dependent Pathway and Stimulate Cell Growth†

(2008) Mi-Hye Lee et al.   BIOCHEMISTRY

The Endosomal Protein Appl1 Mediates Akt Substrate Specificity and Cell Survival in Vertebrate Development

(2008) Annette Schenck et al.   CELL

In Skeletal Muscle Advanced Glycation End Products (AGEs) Inhibit Insulin Action and Induce the Formation of Multimolecular Complexes Including the Receptor for AGEs

(2008) Angela Cassese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY