Up-regulation of Translation Eukaryotic Initiation Factor 4E in Nucleophosmin 1 Haploinsufficient Cells Results in Changes in CCAAT Enhancer-binding Protein α Activity

Targeting Mnks for Cancer Therapy

(2015) Jinqiang Hou et al.   Oncotarget

Protein Phosphatase 2A Negatively Regulates Eukaryotic Initiation Factor 4E Phosphorylation and eIF4F Assembly through Direct Dephosphorylation of Mnk and eIF4E

(2015) Yikun Li et al.   NEOPLASIA

IMiD immunomodulatory compounds block C/EBP  translation through eIF4E down-regulation resulting in inhibition of MM

(2011) S. Li et al.   BLOOD

Acute myeloid leukemia with mutated nucleophosmin (NPM1): Any hope for a targeted therapy?

(2011) Brunangelo Falini et al.   BLOOD REVIEWS

Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

(2010) Christine Müller et al.   EMBO JOURNAL

Regulation and deregulation of mRNA translation during myeloid maturation

(2010) Arati Khanna-Gupta   EXPERIMENTAL HEMATOLOGY

Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML

(2010) J A Pulikkan et al.   LEUKEMIA

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

(2010) L. Furic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired translation of CCAAT/enhancer binding protein α mRNA in bronchial smooth muscle cells of asthmatic patients

(2009) Peter Borger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse

(2008) P. Sportoletti et al.   BLOOD

Sumoylation and the function of CCAAT enhancer binding protein alpha (C/EBPα)

(2008) Arati Khanna-Gupta   BLOOD CELLS MOLECULES AND DISEASES

Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

(2008) Peggy Kirstetter et al.   CANCER CELL

c-Myc and eIF4F Are Components of a Feedforward Loop that Links Transcription and Translation

(2008) C.-J. Lin et al.   CANCER RESEARCH

Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc+ acute myeloid leukemia in SCID mice

(2008) B. Falini et al.   HAEMATOLOGICA

Dysregulation of the C/EBPα Differentiation Pathway in Human Cancer

(2008) Steffen Koschmieder et al.   JOURNAL OF CLINICAL ONCOLOGY

Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA