Sizzled Is Unique among Secreted Frizzled-related Proteins for Its Ability to Specifically Inhibit Bone Morphogenetic Protein-1 (BMP-1)/Tolloid-like Proteinases

Dorsal–Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases

(2011) Diego Ploper et al.   DEVELOPMENTAL BIOLOGY

Metalloproteinases inDrosophilato Humans That Are Central Players in Developmental Processes

(2011) Alison Muir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating Bone Morphogenetic Protein 1-3 Isoform Increases Renal Fibrosis

(2011) L. Grgurevic et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

shRNA targeting SFRP2 promotes the apoptosis of hypertrophic scar fibroblast

(2011) Zhicheng Sun et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Proenzyme Structure and Activation of Astacin Metallopeptidase

(2010) Tibisay Guevara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

sFRP2 Suppression of Bone Morphogenic Protein (BMP) and Wnt Signaling Mediates Mesenchymal Stem Cell (MSC) Self-renewal Promoting Engraftment and Myocardial Repair

(2010) Maria P. Alfaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between Periostin and BMP-1 Promotes Proteolytic Activation of Lysyl Oxidase

(2010) Takumi Maruhashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processing of Procollagen III by Meprins: New Players in Extracellular Matrix Assembly?

(2010) Daniel Kronenberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dentin sialophosphoprotein (DSPP) is cleaved into its two natural dentin matrix products by three isoforms of bone morphogenetic protein-1 (BMP1)

(2010) Zofia von Marschall et al.   MATRIX BIOLOGY

Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

(2010) W. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range

(2009) Y. Mii et al.   DEVELOPMENT

Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase

(2009) Richard Berry et al.   FEBS LETTERS

Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity

(2009) H. X. Lee et al.   GENES & DEVELOPMENT

Robust Stability of the Embryonic Axial Pattern Requires a Secreted Scaffold for Chordin Degradation

(2008) Hidehiko Inomata et al.   CELL

Molecular Determinants of Matrix Metalloproteinase-12 Covalent Modification by a Photoaffinity Probe

(2008) Anne-Sophie Dabert-Gay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

(2008) P. Bovolenta et al.   JOURNAL OF CELL SCIENCE

Structural Basis for the Substrate Specificity of Bone Morphogenetic Protein 1/Tolloid-like Metalloproteases

(2008) A. Mac Sweeney et al.   JOURNAL OF MOLECULAR BIOLOGY

Meprins, membrane-bound and secreted astacin metalloproteinases

(2008) E STERCHI et al.   MOLECULAR ASPECTS OF MEDICINE

Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

(2008) Koichi Kobayashi et al.   NATURE CELL BIOLOGY

The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair

(2008) M. P. Alfaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA