Caspase-mediated Cleavage of RNA-binding Protein HuR Regulates c-Myc Protein Expression after Hypoxic Stress
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Title
Caspase-mediated Cleavage of RNA-binding Protein HuR Regulates c-Myc Protein Expression after Hypoxic Stress
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 286, Issue 37, Pages 32333-32343
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2011-07-28
DOI
10.1074/jbc.m111.255927
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Note: Only part of the references are listed.- The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation
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- c-Myc mediates a hypoxia-induced decrease in acetylated histone H4
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- The Role of HuR in Gemcitabine Efficacy in Pancreatic Cancer: HuR Up-regulates the Expression of the Gemcitabine Metabolizing Enzyme Deoxycytidine Kinase
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- The role of hypoxia-inducible factors in tumorigenesis
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- Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis
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- MKP-1 mRNA Stabilization and Translational Control by RNA-Binding Proteins HuR and NF90
- (2008) Y. Kuwano et al. MOLECULAR AND CELLULAR BIOLOGY
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