Extra-long Gαs Variant XLαs Protein Escapes Activation-induced Subcellular Redistribution and Is Able to Provide Sustained Signaling

Transgenic Overexpression of the Extra-Large Gsα Variant XLαs Enhances Gsα-Mediated Responses in the Mouse Renal Proximal Tubulein Vivo

(2011) Zun Liu et al.   ENDOCRINOLOGY

Retromer terminates the generation of cAMP by internalized PTH receptors

(2011) Timothy N Feinstein et al.   Nature Chemical Biology

Potent constitutive cyclic AMP-generating activity of XLαs implicates this imprinted GNAS product in the pathogenesis of McCune–Albright Syndrome and fibrous dysplasia of bone

(2010) Virginie Mariot et al.   BONE

Integrative epigenomic and genomic analysis of malignant pheochromocytoma

(2010) Johanna Sandgren et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Amplification of GNAS may be an independent, qualitative, and reproducible biomarker to predict progression-free survival in epithelial ovarian cancer

(2010) Ei-ichiro Tominaga et al.   GYNECOLOGIC ONCOLOGY

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

Extralarge XLαs (XXLαs), a Variant of Stimulatory G Protein α-Subunit (Gsα), Is a Distinct, Membrane-AnchoredGNASProduct that Can Mimic Gsα

(2009) Cumhur Aydin et al.   ENDOCRINOLOGY

Cytosolic GαsActs as an Intracellular Messenger to Increase Microtubule Dynamics and Promote Neurite Outgrowth

(2009) Jiang-Zhou Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coupling of  2-Adrenoceptors to XL s and G s: A New Insight into Ligand-Induced G Protein Activation

(2009) A. I. Kaya et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Caveolin-1 and Lipid Microdomains Regulate Gs Trafficking and Attenuate Gs/Adenylyl Cyclase Signaling

(2009) J. A. Allen et al.   MOLECULAR PHARMACOLOGY

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

(2009) Sébastien Ferrandon et al.   Nature Chemical Biology

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

N-terminal polybasic motifs are required for plasma membrane localization of Gαs and Gαq

(2008) Marykate Crouthamel et al.   CELLULAR SIGNALLING

Overall and Relapse-Free Survival in Oropharyngeal and Hypopharyngeal Squamous Cell Carcinoma Are Associated with Genotypes of T393C Polymorphism of the GNAS1 Gene

(2008) G. F. Lehnerdt et al.   CLINICAL CANCER RESEARCH

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation

(2008) M. Okazaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA