Liver-specific Inducible Nitric-oxide Synthase Expression Is Sufficient to Cause Hepatic Insulin Resistance and Mild Hyperglycemia in Mice

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

The Critical Role of AKT2 in Hepatic Steatosis Induced by PTEN Loss

(2010) Lina He et al.   AMERICAN JOURNAL OF PATHOLOGY

Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis

(2010) Takahisa Nakamura et al.   CELL

FoxO1 Links Hepatic Insulin Action to Endoplasmic Reticulum Stress

(2010) Adama Kamagate et al.   ENDOCRINOLOGY

A role of apolipoprotein D in triglyceride metabolism

(2010) German Perdomo et al.   JOURNAL OF LIPID RESEARCH

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance

(2009) Hui-Yu Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Obesity-induced Insulin Resistance and Hyperglycemia

(2009) J A. Jeevendra Martyn et al.   ANESTHESIOLOGY

HOMA1-IR and HOMA2-IR indexes in identifying insulin resistance and metabolic syndrome: Brazilian Metabolic Syndrome Study (BRAMS)

(2009) Bruno Geloneze et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

HIF-1α is necessary to support gluconeogenesis during liver regeneration

(2009) Toshihide Tajima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance

(2009) Karla F. Leavens et al.   Cell Metabolism

Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRβ/IRS-1 and Akt

(2009) M. A. Carvalho-Filho et al.   DIABETOLOGIA

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Aging-Associated Dysfunction of Akt/Protein Kinase B: S-Nitrosylation and Acetaminophen Intervention

(2009) Miaozong Wu et al.   PLoS One

Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

(2009) V. T. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitric Oxide Plays a Crucial Role in the Development/Progression of Nonalcoholic Steatohepatitis in the Choline-Deficient, l-Amino Acid-Defined Diet-Fed Rat Model

(2008) Koji Fujita et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice

(2008) Andrew M. Miller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Acute physical exercise reversesS-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats

(2007) José R. Pauli et al.   JOURNAL OF PHYSIOLOGY-LONDON