The Sterol-sensing Domain (SSD) Directly Mediates Signal-regulated Endoplasmic Reticulum-associated Degradation (ERAD) of 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase Isozyme Hmg2

Identification of Luminal Loop 1 of Scap Protein as the Sterol Sensor That Maintains Cholesterol Homeostasis

(2011) Massoud Motamed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An improved classification of G-protein-coupled receptors using sequence-derived features

(2010) Zhen-Ling Peng et al.   BMC BIOINFORMATICS

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

(2010) Youngah Jo et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Protein Quality Control as a Strategy for Cellular Regulation: Lessons from Ubiquitin-Mediated Regulation of the Sterol Pathway

(2009) Randolph Y. Hampton et al.   CHEMICAL REVIEWS

Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast

(2009) Renee M. Garza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Misfolded Membrane Proteins Are Specifically Recognized by the Transmembrane Domain of the Hrd1p Ubiquitin Ligase

(2009) Brian K. Sato et al.   MOLECULAR CELL

Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP

(2008) Adam L. Hughes et al.   JOURNAL OF LIPID RESEARCH