Structural Basis of Activation of Bitter Taste Receptor T2R1 and Comparison with Class A G-protein-coupled Receptors (GPCRs)

Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β2-adrenergic receptor

(2011) Makoto Arakawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The structural basis of agonist-induced activation in constitutively active rhodopsin

(2011) Jörg Standfuss et al.   NATURE

Structure and Activation of the Visual Pigment Rhodopsin

(2010) Steven O. Smith   Annual Review of Biophysics

Bitter taste receptor T2R1 is activated by dipeptides and tripeptides

(2010) Jasbir Upadhyaya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conserved Water-mediated Hydrogen Bond Network between TM-I, -II, -VI, and -VII in 7TM Receptor Activation

(2010) Rie Nygaard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the β-d-Glucopyranoside Binding Site of the Human Bitter Taste Receptor hTAS2R16

(2010) Takanobu Sakurai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor

(2010) Xevi Biarnés et al.   PLoS One

Structural requirements of bitter taste receptor activation

(2010) A. Brockhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

(2009) Wolfgang Meyerhof et al.   CHEMICAL SENSES

Accelerating molecular dynamic simulation on graphics processing units

(2009) Mark S. Friedrichs et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structural waters define a functional channel mediating activation of the GPCR, rhodopsin

(2009) T. E. Angel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved prediction of protein side-chain conformations with SCWRL4

(2009) Georgii G. Krivov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The Third Intracellular Loop Stabilizes the Inactive State of the Neuropeptide Y1 Receptor

(2008) Melissa J. S. Chee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutational Analysis of the Conserved Asp2.50 and ERY Motif Reveals Signaling Bias of the Urotensin II Receptor

(2008) C. D. Proulx et al.   MOLECULAR PHARMACOLOGY

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

(2008) Michael A. Hanson et al.   STRUCTURE