Translocation of Heme Oxygenase-1 to Mitochondria Is a Novel Cytoprotective Mechanism against Non-steroidal Anti-inflammatory Drug-induced Mitochondrial Oxidative Stress, Apoptosis, and Gastric Mucosal Injury

Heme Oxygenase-1 Protects against Neutrophil-Mediated Intestinal Damage by Down-Regulation of Neutrophil p47phox and p67phox Activity and O2- Production in a Two-Hit Model of Alcohol Intoxication and Burn Injury

(2014) X. Li et al.   JOURNAL OF IMMUNOLOGY

Haem oxygenase-1 and cardiovascular disease: mechanisms and therapeutic potential

(2011) Kim H. Chan et al.   CLINICAL SCIENCE

Preconditioning with cobalt protoporphyrin protects human gastric mucosal cells from deoxycholate-induced apoptosis

(2011) Tina E. Lawson et al.   WOUND REPAIR AND REGENERATION

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Neuroprotective Mechanism of Mitochondrial Ferritin on 6-Hydroxydopamine–Induced Dopaminergic Cell Damage: Implication for Neuroprotection in Parkinson's Disease

(2010) Zhen-Hua Shi et al.   ANTIOXIDANTS & REDOX SIGNALING

Sofalcone, a gastric mucosa protective agent, increases vascular endothelial growth factor via the Nrf2-heme-oxygenase-1 dependent pathway in gastric epithelial cells

(2010) Akiko Shibuya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gastroprotective effect of heme-oxygenase 1/biliverdin/CO pathway in ethanol-induced gastric damage in mice

(2010) Antoniella S. Gomes et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gallic acid prevents nonsteroidal anti-inflammatory drug-induced gastropathy in rat by blocking oxidative stress and apoptosis

(2010) Chinmay Pal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Heme Oxygenase-1 Protein Expression by miR-377 in Combination with miR-217

(2010) Joan D. Beckman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of esomeprazole on healing of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: Characterization of molecular mechanisms

(2010) Matteo Fornai et al.   PHARMACOLOGICAL RESEARCH

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

(2010) D. R. Richardson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review article: cellular and molecular mechanisms of NSAID-induced peptic ulcers

(2009) C. MUSUMBA et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Heme Degradation and Vascular Injury

(2009) John D. Belcher et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia

(2009) Ju-Young Kim et al.   CARDIOVASCULAR RESEARCH

Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease

(2009) Danielle Morse et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins

(2009) Weihong Hou et al.   HEPATOLOGY

Mitochondria-Derived Reactive Oxygen Species Mediate Heme Oxygenase-1 Expression in Sheared Endothelial Cells

(2009) Z. Han et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Lansoprazole, a Proton Pump Inhibitor, Mediates Anti-Inflammatory Effect in Gastric Mucosal Cells through the Induction of Heme Oxygenase-1 via Activation of NF-E2-Related Factor 2 and Oxidation of Kelch-Like ECH-Associating Protein 1

(2009) T. Takagi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Melatonin reduces indomethacin-induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis

(2009) Pallab Maity et al.   JOURNAL OF PINEAL RESEARCH

Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

(2009) E. Seixas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

PROTECTIVE ROLE OF HEME OXYGENASE 1 IN THE INTESTINAL TISSUE INJURY IN HEMORRHAGIC SHOCK IN RATS

(2009) Kazuyoshi Inoue et al.   SHOCK

Nrf2 signaling and cell survival

(2009) Suryakant K. Niture et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Heme Oxygenase-1: Its Therapeutic Roles in Inflammatory Diseases

(2009) Hyun-Ock Pae et al.   Immune Network

Targeting Mitochondria

(2008) Adam T. Hoye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Adaptive HNE-Nrf2-HO-1 pathway against oxidative stress is associated with acute gastric mucosal lesions

(2008) Kazuki Ueda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

(2008) A. Campanella et al.   HUMAN MOLECULAR GENETICS

Indomethacin, a Non-steroidal Anti-inflammatory Drug, Develops Gastropathy by Inducing Reactive Oxygen Species-mediated Mitochondrial Pathology and Associated Apoptosis in Gastric Mucosa

(2008) Pallab Maity et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lansoprazole Protects and Heals Gastric Mucosa from Non-steroidal Anti-inflammatory Drug (NSAID)-induced Gastropathy by Inhibiting Mitochondrial as Well as Fas-mediated Death Pathways with Concurrent Induction of Mucosal Cell Renewal

(2008) Pallab Maity et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A central role for free heme in the pathogenesis of severe malaria: the missing link?

(2008) Ana Ferreira et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Isolation of mitochondria from rat brain using Percoll density gradient centrifugation

(2008) Neil R Sims et al.   Nature Protocols

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

(2007) E. Olatunde Farombi et al.   FOOD AND CHEMICAL TOXICOLOGY