Lung Tumor-associated Osteoblast-derived Bone Morphogenetic Protein-2 Increased Epithelial-to-Mesenchymal Transition of Cancer by Runx2/Snail Signaling Pathway

The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs

(2011) Robert R. Langley et al.   INTERNATIONAL JOURNAL OF CANCER

The p38/MK2/Hsp25 Pathway Is Required for BMP-2-Induced Cell Migration

(2011) Cristina Gamell et al.   PLoS One

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

The bone remodeling environment is a factor in breast cancer bone metastasis

(2010) Li Laine Ooi et al.   BONE

TGF-β in cancer and bone: Implications for treatment of bone metastases

(2010) Patricia Juárez et al.   BONE

Runx2 in human breast carcinoma: its potential roles in cancer progression

(2010) Yoshiaki Onodera et al.   CANCER SCIENCE

Metastasis and bone loss: Advancing treatment and prevention

(2010) Robert E. Coleman et al.   CANCER TREATMENT REVIEWS

Prognostic Impact of Vascular Endothelial Growth Factor-A and E-Cadherin Expression in Completely Resected Pathologic Stage I Non-Small Cell Lung Cancer

(2010) Q. Lin et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Parathyroid Hormone Activation of Matrix Metalloproteinase-13 Transcription Requires the Histone Acetyltransferase Activity of p300 and PCAF and p300-dependent Acetylation of PCAF

(2010) Minnkyong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMP2-activated Erk/MAP Kinase Stabilizes Runx2 by Increasing p300 Levels and Histone Acetyltransferase Activity

(2010) Ji Hae Jun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL5/ENA78 increased cell migration and epithelial-to-mesenchymal transition of hormone-independent prostate cancer by early growth response-1/snail signaling pathway

(2010) Po-Lin Kuo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice

(2010) Matthew B. Greenblatt et al.   JOURNAL OF CLINICAL INVESTIGATION

Snail nuclear expression parallels higher malignancy potential in neuroendocrine lung tumors

(2010) J.A. Galván et al.   LUNG CANCER

Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

(2010) Sanjeev K Baniwal et al.   Molecular Cancer

Future directions of bone-targeted therapy for metastatic breast cancer

(2010) Tomifumi Onishi et al.   Nature Reviews Clinical Oncology

The Tumor Microenvironment in Non–Small-Cell Lung Cancer

(2010) Edward E. Graves et al.   SEMINARS IN RADIATION ONCOLOGY

Tumor-Stromal Interactions in Bone Metastasis

(2010) Kalyan C. Nannuru et al.   Current Osteoporosis Reports

Snail Promotes CXCR2 Ligand-Dependent Tumor Progression in Non-Small Cell Lung Carcinoma

(2009) J. Yanagawa et al.   CLINICAL CANCER RESEARCH

FGF2-activated ERK Mitogen-activated Protein Kinase Enhances Runx2 Acetylation and Stabilization

(2009) Ok-Jin Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone morphogenetic protein-2 levels are elevated in the patients with gastric cancer and correlate with disease progression

(2009) Yong Park et al.   MEDICAL ONCOLOGY

Runx2 Recruits p300 to Mediate Parathyroid Hormone’s Effects on Histone Acetylation and Transcriptional Activation of the Matrix Metalloproteinase-13 Gene

(2009) Christine E. Boumah et al.   MOLECULAR ENDOCRINOLOGY

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

(2009) J Akech et al.   ONCOGENE

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

(2008) J. Pratap et al.   CANCER RESEARCH

Curcumin Inhibits Lung Cancer Cell Invasion and Metastasis through the Tumor Suppressor HLJ1

(2008) H.-W. Chen et al.   CANCER RESEARCH

Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2

(2008) Kelly J. Gordon et al.   CARCINOGENESIS

Proteases and bone remodelling

(2008) S. Georges et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

Transcriptional regulation of cell polarity in EMT and cancer

(2008) G Moreno-Bueno et al.   ONCOGENE

Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins

(2008) Tzu-Hsiu Lai et al.   PROSTATE

PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-κB in metastatic prostate cancer cells

(2008) Tisheeka R. Graham et al.   PROSTATE