The p73 Tumor Suppressor Is Targeted by Pirh2 RING Finger E3 Ubiquitin Ligase for the Proteasome-dependent Degradation

A novel oncoprotein Pirh2: rising from the shadow of MDM2

(2011) Zhihao Wang et al.   CANCER SCIENCE

Expression of Pirh2, a p27Kip1 ubiquitin ligase, in hepatocellular carcinoma: correlation with p27Kip1 and cell proliferation

(2011) Xiaodong Huang et al.   HUMAN PATHOLOGY

Isoform-specific p73 knockout mice reveal a novel role for  Np73 in the DNA damage response pathway

(2010) M. T. Wilhelm et al.   GENES & DEVELOPMENT

High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers

(2009) Mai Shimada et al.   CANCER SCIENCE

Pirh2 E3 Ubiquitin Ligase Targets DNA Polymerase Eta for 20S Proteasomal Degradation

(2009) Y.-S. Jung et al.   MOLECULAR AND CELLULAR BIOLOGY

The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73

(2009) A Peschiaroli et al.   ONCOGENE

Therapeutic prospects for p73 and p63: Rising from the shadow of p53

(2008) Anna Vilgelm et al.   DRUG RESISTANCE UPDATES

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT