Protein Kinase Cθ Is a Specific Target for Inhibition of the HIV Type 1 Replication in CD4+T Lymphocytes

Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCθ inhibitors

(2010) Diane H. Boschelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New Insights into the Mechanisms whereby Low Molecular Weight CCR5 Ligands Inhibit HIV-1 Infection

(2010) Javier Garcia-Perez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of the new immunosuppressive agent AEB071 on human immune cells

(2010) M. Matz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon

(2010) M. R. Lopez-Huertas et al.   NUCLEIC ACIDS RESEARCH

PKC inhibitors: potential in T cell-dependent immune diseases

(2009) Gottfried Baier et al.   CURRENT OPINION IN CELL BIOLOGY

Small Molecule Inhibitors of PKCθ as Potential Antiinflammatory Therapeutics

(2009) Diane Boschelli   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

(2009) J.-P. Evenou et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

(2009) Mayte Coiras et al.   NATURE REVIEWS MICROBIOLOGY

SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro

(2008) Luis M. Bedoya et al.   BIOCHEMICAL PHARMACOLOGY

Spatiotemporal dynamics of lipid signaling: Protein kinase C as a paradigm

(2008) Lisa L. Gallegos et al.   IUBMB LIFE

Lipid activation of protein kinases

(2008) Alexandra C. Newton   JOURNAL OF LIPID RESEARCH

Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV

(2008) P. A. Wender et al.   SCIENCE

Differential effects of phorbol-13-monoesters on human immunodeficiency virus reactivation

(2007) Nieves Márquez et al.   BIOCHEMICAL PHARMACOLOGY