Quantitative Cell-based Protein Degradation Assays to Identify and Classify Drugs That Target the Ubiquitin-Proteasome System

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

(2011) T.-F. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase

(2010) Mariam Aghajan et al.   NATURE BIOTECHNOLOGY

Identification of a Primary Target of Thalidomide Teratogenicity

(2010) T. Ito et al.   SCIENCE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Therapeutic strategies within the ubiquitin proteasome system

(2009) A G Eldridge et al.   CELL DEATH AND DIFFERENTIATION

Cytomegalovirus Promoter Up-regulation Is the Major Cause of Increased Protein Levels of Unstable Reporter Proteins after Treatment of Living Cells with Proteasome Inhibitors

(2009) Beatriz Alvarez-Castelao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Conserved Unfoldase Activity for the p97 AAA-ATPase in Proteasomal Degradation

(2009) Anne Beskow et al.   JOURNAL OF MOLECULAR BIOLOGY

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Targeting proteins for degradation

(2009) Erin K Schrader et al.   Nature Chemical Biology

Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer

(2008) Sharmila Patel et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Inhibition of p97-dependent Protein Degradation by Eeyarestatin I

(2008) Qiuyan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired Protein Aggregate Handling and Clearance Underlie the Pathogenesis of p97/VCP-associated Disease

(2008) Jeong-Sun Ju et al.   JOURNAL OF BIOLOGICAL CHEMISTRY