Interaction of the Influenza A Virus Polymerase PB2 C-terminal Region with Importin α Isoforms Provides Insights into Host Adaptation and Polymerase Assembly

Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit

(2011) Franck Tarendeau et al.   PLoS Pathogens

Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin-α Using Oriented Peptide Library Screening

(2010) Sundy N. Y. Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influenza A Virus Polymerase: Structural Insights into Replication and Host Adaptation Mechanisms

(2010) Stéphane Boivin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase

(2010) O. Moncorge et al.   JOURNAL OF VIROLOGY

Association of the Influenza Virus RNA Polymerase Subunit PB2 with the Host Chaperonin CCT

(2010) T. Fislova et al.   JOURNAL OF VIROLOGY

Complete-Proteome Mapping of Human Influenza A Adaptive Mutations: Implications for Human Transmissibility of Zoonotic Strains

(2010) Olivo Miotto et al.   PLoS One

Role of Importin Alpha8, a New Member of the Importin Alpha Family of Nuclear Transport Proteins, in Early Embryonic Development in Cattle1

(2009) Jyothsna Tejomurtula et al.   BIOLOGY OF REPRODUCTION

Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase

(2009) Kanako Sugiyama et al.   EMBO JOURNAL

Structural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 Residue

(2009) Takashi Kuzuhara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Import and Assembly of Influenza A Virus RNA Polymerase Studied in Live Cells by Fluorescence Cross-Correlation Spectroscopy

(2009) S. Huet et al.   JOURNAL OF VIROLOGY

Different Evolutionary Trajectories of European Avian-Like and Classical Swine H1N1 Influenza A Viruses

(2009) E. J. Dunham et al.   JOURNAL OF VIROLOGY

Selection of H5N1 Influenza Virus PB2 during Replication in Humans

(2009) Q. M. Le et al.   JOURNAL OF VIROLOGY

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Changes in Selective Constraints: Host Shifts in Influenza

(2009) Asif U. Tamuri et al.   PLoS Computational Biology

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Host Restriction of Avian Influenza Viruses at the Level of the Ribonucleoproteins

(2008) Nadia Naffakh et al.   Annual Review of Microbiology

Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis

(2008) Olivo Miotto et al.   BMC BIOINFORMATICS

An Inhibitory Activity in Human Cells Restricts the Function of an Avian-like Influenza Virus Polymerase

(2008) Andrew Mehle et al.   Cell Host & Microbe

Crystal structure of the polymerase PAC–PB1N complex from an avian influenza H5N1 virus

(2008) Xiaojing He et al.   NATURE

The structural basis for an essential subunit interaction in influenza virus RNA polymerase

(2008) Eiji Obayashi et al.   NATURE

The structural basis for cap binding by influenza virus polymerase subunit PB2

(2008) Delphine Guilligay et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Host-Dependent Interaction of α-Importins with Influenza PB2 Polymerase Subunit Is Required for Virus RNA Replication

(2008) Patricia Resa-Infante et al.   PLoS One

Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus

(2008) Gülsah Gabriel et al.   PLoS Pathogens