Src Homology Domain 2-containing Protein-tyrosine Phosphatase-1 (SHP-1) Binds and Dephosphorylates Gα-interacting, Vesicle-associated Protein (GIV)/Girdin and Attenuates the GIV-Phosphatidylinositol 3-Kinase (PI3K)-Akt Signaling Pathway

The Actin-Binding Protein Girdin and Its Akt-Mediated Phosphorylation Regulate Neointima Formation After Vascular Injury

(2011) Hiroshi Miyake et al.   CIRCULATION RESEARCH

A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

(2011) Mikel Garcia-Marcos et al.   MOLECULAR BIOLOGY OF THE CELL

GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression

(2011) Pradipta Ghosh et al.   Cell Adhesion & Migration

Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer

(2010) Mikel Garcia-Marcos et al.   FASEB JOURNAL

A Structural Determinant That Renders GαiSensitive to Activation by GIV/Girdin Is Required to Promote Cell Migration

(2010) Mikel Garcia-Marcos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Gαi–GIV Molecular Complex Binds Epidermal Growth Factor Receptor and Determines Whether Cells Migrate or Proliferate

(2010) Pradipta Ghosh et al.   MOLECULAR BIOLOGY OF THE CELL

Role of the protein tyrosine phosphatase SHP-1 in Interleukin-6 regulation of prostate cancer cells

(2010) Helena Tassidis et al.   PROSTATE

Interplay between the heterotrimeric G-protein subunits Gαq and Gαi2 sets the threshold for chemotaxis and TCR activation

(2009) Jacob Ngai et al.   BMC IMMUNOLOGY

How DISC1 Regulates Postnatal Brain Development: Girdin Gets In on the AKT

(2009) David Porteous et al.   NEURON

Roles of Disrupted-In-Schizophrenia 1-Interacting Protein Girdin in Postnatal Development of the Dentate Gyrus

(2009) Atsushi Enomoto et al.   NEURON

GIV is a nonreceptor GEF for G i with a unique motif that regulates Akt signaling

(2009) M. Garcia-Marcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central Neuroinvasion and Demyelination by Inflammatory Macrophages After Peripheral Virus Infection is Controlled by SHP-1

(2009) George P. Christophi et al.   VIRAL IMMUNOLOGY

An Actin-Binding Protein Girdin Regulates the Motility of Breast Cancer Cells

(2008) P. Jiang et al.   CANCER RESEARCH

Activation of Gαi3 triggers cell migration via regulation of GIV

(2008) Pradipta Ghosh et al.   JOURNAL OF CELL BIOLOGY

Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin

(2008) Tomoya Kitamura et al.   NATURE CELL BIOLOGY