The Antagonistic Action of B56-containing Protein Phosphatase 2As and Casein Kinase 2 Controls the Phosphorylation and Gli Turnover Function of Daz Interacting Protein 1

Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish

(2010) Hyejeong Kim et al.   BMC BIOLOGY

Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

(2010) C. Wang et al.   DEVELOPMENT

PP2A:B56ϵ, a Substrate ofCaspase-3, Regulatesp53-dependent andp53-independent Apoptosis during Development

(2010) Zhigang Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Casein Kinase 2 Promotes Hedgehog Signaling by Regulating both Smoothened and Cubitus Interruptus

(2010) Hongge Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions of B56-containing PP2As in major developmental and cancer signaling pathways

(2010) Jing Yang et al.   LIFE SCIENCES

Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal

(2010) L Di Marcotullio et al.   ONCOGENE

The Zn Finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis

(2009) Andrew M. Glazer et al.   DEVELOPMENTAL BIOLOGY

The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis

(2009) Shang Yew Tay et al.   DEVELOPMENTAL DYNAMICS

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

(2009) M.-H. Chen et al.   GENES & DEVELOPMENT

The 48-kDa Alternative Translation Isoform of PP2A:B56ϵ Is Required for Wnt Signaling during Midbrain-Hindbrain Boundary Formation

(2009) Zhigang Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From Promiscuity to Precision: Protein Phosphatases Get a Makeover

(2009) David M. Virshup et al.   MOLECULAR CELL

Point Mutations in GLI3 Lead to Misregulation of its Subcellular Localization

(2009) Sybille Krauß et al.   PLoS One

Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase

(2009) Qing Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

hnRNP I Inhibits Notch Signaling and Regulates Intestinal Epithelial Homeostasis in the Zebrafish

(2009) Jing Yang et al.   PLoS Genetics

Protein Phosphatase 2A and Rapamycin Regulate the Nuclear Localization and Activity of the Transcription Factor GLI3

(2008) S. Krauss et al.   CANCER RESEARCH

PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation

(2008) H. Jia et al.   DEVELOPMENT

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL