Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds

Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase fromYersinia pseudotuberculosis

(2010) Mads Gabrielsen et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Statistical molecular design of a focused salicylidene acylhydrazide library and multivariate QSAR of inhibition of type III secretion in the Gram-negative bacterium Yersinia

(2010) Markus K. Dahlgren et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Statistical Molecular Design of Balanced Compound Libraries for QSAR Modeling

(2010) A. Linusson et al.   CURRENT MEDICINAL CHEMISTRY

Antivirulence drugs to target bacterial secretion systems

(2010) Christian Baron   CURRENT OPINION IN MICROBIOLOGY

Candidate vaginal microbicides with activity against Chlamydia trachomatis and Neisseriagonorrhoeae

(2010) Hencelyn Chu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Thiol Peroxidase Protects Salmonella enterica from Hydrogen Peroxide Stress In Vitro and Facilitates Intracellular Growth

(2010) S. A. Horst et al.   JOURNAL OF BACTERIOLOGY

Synthesis of 2-(2-Aminopyrimidine)-2,2-difluoroethanols as Potential Bioisosters of Salicylidene Acylhydrazides

(2010) Markus K. Dahlgren et al.   MOLECULES

Synthesis of [4-(2-Hydroxyphenyl)thiazol-2-yl]methanones as Potential Bioisosteres of Salicylidene Acylhydrazides

(2010) J. Mikael Hillgren et al.   MOLECULES

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Structure-based discovery of antibacterial drugs

(2010) Katie J. Simmons et al.   NATURE REVIEWS MICROBIOLOGY

Using Small Molecules To Dissect Mechanisms of Microbial Pathogenesis

(2009) Aaron W. Puri et al.   ACS Chemical Biology

Designing Multiple Ligands – Medicinal Chemistry Strategies and Challenges

(2009) Richard Morphy et al.   CURRENT PHARMACEUTICAL DESIGN

Characterization of the Effects of Salicylidene Acylhydrazide Compounds on Type III Secretion in Escherichia coli O157:H7

(2009) J. J. Tree et al.   INFECTION AND IMMUNITY

Structural Changes Common to Catalysis in the Tpx Peroxiredoxin Subfamily

(2009) Andrea Hall et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of the cellular targets of bioactive small organic molecules using affinity reagents

(2008) Benjamin J. Leslie et al.   CHEMICAL SOCIETY REVIEWS

Antivirulence as a new antibacterial approach for chemotherapy

(2008) Sonia Escaich   CURRENT OPINION IN CHEMICAL BIOLOGY

Novel strategies to combat bacterial virulence

(2008) Susan V Lynch et al.   Current Opinion in Critical Care

Mapping short DNA sequencing reads and calling variants using mapping quality scores

(2008) H. Li et al.   GENOME RESEARCH

Small-Molecule Type III Secretion System Inhibitors Block Assembly of the Shigella Type III Secreton

(2008) A. K. J. Veenendaal et al.   JOURNAL OF BACTERIOLOGY

Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria

(2008) P. Keyser et al.   JOURNAL OF INTERNAL MEDICINE

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY