Testing the Therapeutic Potential of Doxycycline in aDrosophila melanogasterModel of Alzheimer Disease

The presence of sodium dodecyl sulphate-stable Aβ dimers is strongly associated with Alzheimer-type dementia

(2010) Jessica M. Mc Donald et al.   BRAIN

RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10

(2010) Gizem Donmez et al.   CELL

Bepridil and Amiodarone Simultaneously Target the Alzheimer's Disease  - and  -Secretase via Distinct Mechanisms

(2010) S. Mitterreiter et al.   JOURNAL OF NEUROSCIENCE

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

(2010) Isabel Cardoso et al.   Journal of Translational Medicine

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers

(2010) Luisa Diomede et al.   NEUROBIOLOGY OF DISEASE

Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction

(2010) Cristina Airoldi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Complete Phenotypic Recovery of an Alzheimer's Disease Model by a Quinone-Tryptophan Hybrid Aggregation Inhibitor

(2010) Roni Scherzer-Attali et al.   PLoS One

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

(2009) Katharina Faust et al.   BMC NEUROSCIENCE

Amyloid-β fibrillogenesis: Structural insight and therapeutic intervention

(2009) Kevin A. DaSilva et al.   EXPERIMENTAL NEUROLOGY

β-amyloid oligomers and cellular prion protein in Alzheimer’s disease

(2009) Erik C. Gunther et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses

(2009) Efrat Abramov et al.   NATURE NEUROSCIENCE

Alzheimer's disease: insights from Drosophila melanogaster models

(2009) Aileen Moloney et al.   TRENDS IN BIOCHEMICAL SCIENCES

Modulatory effect of acetyl-l-carnitine on amyloid precursor protein metabolism in hippocampal neurons

(2008) Roberta Epis et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity

(2008) R. Costa et al.   FEBS LETTERS

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

(2008) Sanjay W. Pimplikar   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE