The Small GTPase Cdc42 Interacts with Niemann-Pick C1-like 1 (NPC1L1) and Controls Its Movement from Endocytic Recycling Compartment to Plasma Membrane in a Cholesterol-dependent Manner

The N-terminal Domain of NPC1L1 Protein Binds Cholesterol and Plays Essential Roles in Cholesterol Uptake

(2011) Jin-Hui Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Characterization of the NPC1L1 Variants Identified from Cholesterol Low Absorbers

(2010) Li-Juan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake

(2010) L. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdc42 and Vesicle Trafficking in Polarized Cells

(2010) Kathryn P. Harris et al.   TRAFFIC

Requirement of Myosin Vb·Rab11a·Rab11-FIP2 Complex in Cholesterol-regulated Translocation of NPC1L1 to the Cell Surface

(2009) Bei-Bei Chu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid

(2009) Benny Liu et al.   JOURNAL OF LIPID RESEARCH

In-vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbers

(2009) Yoshihide Yamanashi et al.   Pharmacogenetics and Genomics

The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

(2008) Liang Ge et al.   Cell Metabolism

Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice

(2008) Haixin Yuan et al.   HEPATOLOGY

Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes

(2008) Saleemah Fahmi et al.   HUMAN MOLECULAR GENETICS