Local Elongation of Endothelial Cell-anchored von Willebrand Factor Strings Precedes ADAMTS13 Protein-mediated Proteolysis

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus)

(2010) H. B. Feys et al.   BLOOD

Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro

(2010) Anyou Wang et al.   THROMBOSIS RESEARCH

Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura

(2009) H. B. Feys et al.   BLOOD

Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage

(2009) N. A. Turner et al.   BLOOD

von Willebrand factor to the rescue

(2009) S. F. De Meyer et al.   BLOOD

Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells

(2009) M. van den Biggelaar et al.   HAEMATOLOGICA

von Willebrand factor cleaved from endothelial cells by ADAMTS13 remains ultralarge in size

(2009) S.-Y. JIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Multi-step binding of ADAMTS-13 to von Willebrand factor

(2009) H. B. FEYS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Integrin  v 3 on human endothelial cells binds von Willebrand factor strings under fluid shear stress

(2008) J. Huang et al.   BLOOD

Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions

(2008) Y. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ADAMTS-13 cleaves long von Willebrand factor multimeric strings anchored to endothelial cells in the absence of flow, platelets or conformation-altering chemicals

(2008) N. TURNER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Assembly of Weibel Palade body-like tubules from N-terminal domains of von Willebrand factor

(2008) R.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress

(2007) K. Shim et al.   BLOOD