Molecular Dissection of Cl−-selective Cys-loop Receptor Points to Components That Are Dispensable or Essential for Channel Activity

In Glycine and GABAAChannels, Different Subunits Contribute Asymmetrically to Channel Conductance via Residues in the Extracellular Domain

(2011) Mirko Moroni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Relationships between Agonist Binding Sites and Coupling Regions of Homomeric Cys-Loop Receptors

(2011) N. Andersen et al.   JOURNAL OF NEUROSCIENCE

Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors

(2011) Gisela D. Cymes et al.   NATURE

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC

(2011) Iwan Zimmermann et al.   PLOS BIOLOGY

Probing Pore Constriction in a Ligand-gated Ion Channel by Trapping a Metal Ion in the Pore upon Agonist Dissociation

(2010) Ilya Pittel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bridging the Gap between Structural Models of Nicotinic Receptor Superfamily Ion Channels and Their Corresponding Functional States

(2010) Giovanni Gonzalez-Gutierrez et al.   JOURNAL OF MOLECULAR BIOLOGY

The structural basis of function in Cys-loop receptors

(2010) Andrew J. Thompson et al.   QUARTERLY REVIEWS OF BIOPHYSICS

[3H]Chlorpromazine Photolabeling of theTorpedoNicotinic Acetylcholine Receptor Identifies Two State-Dependent Binding Sites in the Ion Channel

(2009) David C. Chiara et al.   BIOCHEMISTRY

Nicotinic receptors and nicotine addiction

(2009) Jean-Pierre Changeux   COMPTES RENDUS BIOLOGIES

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

(2009) Ryan E Hibbs et al.   EMBO JOURNAL

Multifunctional Basic Motif in the Glycine Receptor Intracellular Domain Induces Subunit-specific Sorting

(2009) Nima Melzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the Origin of Ion Selectivity in the Cys-Loop Receptor Family

(2009) Steven M. Sine et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors

(2009) D. Rayes et al.   JOURNAL OF NEUROSCIENCE

Time-Resolved Photolabeling of the Nicotinic Acetylcholine Receptor by [3H]Azietomidate, an Open-State Inhibitor

(2009) D. C. Chiara et al.   MOLECULAR PHARMACOLOGY

Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in α1 Glycine Receptor Channels

(2008) Jane E. Carland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance

(2008) Scott B. Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modular Design of Cys-loop Ligand-gated Ion Channels: Functional 5-HT3and GABA ρ1 Receptors Lacking the Large Cytoplasmic M3M4 Loop

(2008) Michaela Jansen et al.   JOURNAL OF GENERAL PHYSIOLOGY

The Interface between Extracellular and Transmembrane Domains of Homomeric Cys-Loop Receptors Governs Open-Channel Lifetime and Rate of Desensitization

(2008) C. Bouzat et al.   JOURNAL OF NEUROSCIENCE

Trafficking of 5-HT3and GABAAreceptors (Review)

(2008) C. N. Connolly   MOLECULAR MEMBRANE BIOLOGY

Assembly and trafficking of nicotinic acetylcholine receptors (Review)

(2008) Neil S. Millar et al.   MOLECULAR MEMBRANE BIOLOGY

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY