γ-Secretase and Presenilin Mediate Cleavage and Phosphorylation of Vascular Endothelial Growth Factor Receptor-1

When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus

(2011) Sung Hee Baek   MOLECULAR CELL

Placenta Growth Factor-1 Exerts Time-Dependent Stabilization of Adherens Junctions Following VEGF-Induced Vascular Permeability

(2011) Jun Cai et al.   PLoS One

PEDF Regulates Vascular Permeability by a γ-Secretase-Mediated Pathway

(2011) Jun Cai et al.   PLoS One

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates

(2010) Allen C. Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines

(2010) David M Markusic et al.   MOLECULAR THERAPY

Proteases and sFlt-1 Release in the Human Placenta

(2010) S. Zhao et al.   PLACENTA

Identification of Ligand-Induced Proteolytic Cleavage and Ectodomain Shedding of VEGFR-1/FLT1 in Leukemic Cancer Cells

(2009) N. Rahimi et al.   CANCER RESEARCH

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

(2009) Sofie Mellberg et al.   FASEB JOURNAL

Down-Regulation of the Met Receptor Tyrosine Kinase by Presenilin-dependent Regulated Intramembrane Proteolysis

(2009) Bénédicte Foveau et al.   MOLECULAR BIOLOGY OF THE CELL

γ-Secretase in biology and medicine

(2009) Michael S. Wolfe   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ADAM10 Regulates Endothelial Permeability and T-Cell Transmigration by Proteolysis of Vascular Endothelial Cadherin

(2008) Beate Schulz et al.   CIRCULATION RESEARCH

γ-Secretase: a multifaceted regulator of angiogenesis

(2008) Michael E. Boulton et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF

(2008) Astrid F. Nottebaum et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE