Disruption of the Murine Protein Kinase Cβ Gene Promotes Gallstone Formation and Alters Biliary Lipid and Hepatic Cholesterol Metabolism

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin

(2010) Takashi Yamamoto et al.   JOURNAL OF LIPID RESEARCH

Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation

(2009) J. Miao et al.   GENES & DEVELOPMENT

Loss of protein kinase Cβ function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance

(2009) Wei Huang et al.   HEPATOLOGY

Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism inApobec-1−/−Mice Lead to Increased Gallstone Susceptibility

(2009) Yan Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice

(2009) Yan Xie et al.   JOURNAL OF LIPID RESEARCH

Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression

(2008) Kwang-Hoon Song et al.   HEPATOLOGY

Protein kinase C α modulates liver X receptor α transactivation

(2008) Christopher J Delvecchio et al.   JOURNAL OF ENDOCRINOLOGY

Biliary lipids and cholesterol gallstone disease

(2008) David Q-H. Wang et al.   JOURNAL OF LIPID RESEARCH

Phosphorylation of Farnesoid X Receptor by Protein Kinase C Promotes Its Transcriptional Activity

(2008) Romain Gineste et al.   MOLECULAR ENDOCRINOLOGY

Hepatic insulin resistance directly promotes formation of cholesterol gallstones

(2008) Sudha B Biddinger et al.   NATURE MEDICINE

Identification of a functional protein kinase Cβ promoter polymorphism in humans related to insulin resistance

(2007) Martin A. Osterhoff et al.   MOLECULAR GENETICS AND METABOLISM