The Breast Cancer Susceptibility GeneBRCA2Is Required for the Maintenance of Telomere Homeostasis

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage

(2011) Thomas Göhler et al.   JOURNAL OF CELL BIOLOGY

Germline Brca2 Heterozygosity Promotes KrasG12D -Driven Carcinogenesis in a Murine Model of Familial Pancreatic Cancer

(2010) Ferdinandos Skoulidis et al.   CANCER CELL

Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells

(2010) S. Lekomtsev et al.   JOURNAL OF CELL SCIENCE

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Alternative lengthening of telomeres: models, mechanisms and implications

(2010) Anthony J. Cesare et al.   NATURE REVIEWS GENETICS

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

(2010) Sophie Badie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

(2010) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis

(2009) Eunhee Choi et al.   EMBO JOURNAL

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

(2009) Angela Rizzo et al.   NUCLEIC ACIDS RESEARCH

The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation

(2009) John P Alao et al.   Radiation Oncology

Short Telomeres Initiate Telomere Recombination in Primary and Tumor Cells

(2009) Tammy A. Morrish et al.   PLoS Genetics

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Linking the Cellular Functions of BRCA Genes to Cancer Pathogenesis and Treatment

(2008) Ashok R. Venkitaraman   Annual Review of Pathology-Mechanisms of Disease

Genomic Stability: FANCJ-Dependent G4 DNA Repair

(2008) Nancy Maizels   CURRENT BIOLOGY

Chk1 and Claspin potentiate PCNA ubiquitination

(2008) X. H. Yang et al.   GENES & DEVELOPMENT

DNA damage response at functional and dysfunctional telomeres

(2008) M. P. Longhese   GENES & DEVELOPMENT

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

(2008) Y. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY