Dual Phosphorylation of Suppressor of Fused (Sufu) by PKA and GSK3β Regulates Its Stability and Localization in the Primary Cilium
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Title
Dual Phosphorylation of Suppressor of Fused (Sufu) by PKA and GSK3β Regulates Its Stability and Localization in the Primary Cilium
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 286, Issue 15, Pages 13502-13511
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2011-02-12
DOI
10.1074/jbc.m110.217604
References
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Related references
Note: Only part of the references are listed.- Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors
- (2010) C. Wang et al. DEVELOPMENT
- Mechanism and evolution of cytosolic Hedgehog signal transduction
- (2010) C. W. Wilson et al. DEVELOPMENT
- The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
- (2010) E. W. Humke et al. GENES & DEVELOPMENT
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- Sufu recruits GSK3β for efficient processing of Gli3
- (2009) Yoshiaki Kise et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
- (2009) M.-H. Chen et al. GENES & DEVELOPMENT
- Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
- (2009) Ljiljana Milenkovic et al. JOURNAL OF CELL BIOLOGY
- Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis
- (2009) Christopher W. Wilson et al. NATURE
- Photoactivatable mCherry for high-resolution two-color fluorescence microscopy
- (2009) Fedor V Subach et al. NATURE METHODS
- Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia
- (2009) Michael A. Silverman et al. TRENDS IN CELL BIOLOGY
- Therapeutic Inhibition of Hedgehog-GLI Signaling in Cancer: Epithelial, Stromal, or Stem Cell Targets?
- (2008) Ariel Ruiz i Altaba CANCER CELL
- Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
- (2008) Salvatore Cortellino et al. DEVELOPMENTAL BIOLOGY
- Hedgehog Signaling in Development and Cancer
- (2008) Jin Jiang et al. DEVELOPMENTAL CELL
- Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin–proteasome pathway
- (2008) S Yue et al. ONCOGENE
- -Arrestin-Mediated Localization of Smoothened to the Primary Cilium
- (2008) J. J. Kovacs et al. SCIENCE
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