Human Cyclooxygenase-2 Is a Sequence Homodimer That Functions as a Conformational Heterodimer

Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk

(2011) Artemis P Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE

Emotion Recollected in Tranquility: Lessons Learned from the COX-2 Saga

(2010) Tilo Grosser et al.   Annual Review of Medicine

Comparison of Cyclooxygenase-1 Crystal Structures: Cross-Talk between Monomers Comprising Cyclooxygenase-1 Homodimers,

(2010) Ranjinder S. Sidhu et al.   BIOCHEMISTRY

Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2

(2010) Alex J. Vecchio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FADSgenetic variants and ω-6 polyunsaturated fatty acid metabolism in a homogeneous island population

(2010) Rasika A. Mathias et al.   JOURNAL OF LIPID RESEARCH

Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

(2010) N. P. Sharma et al.   MOLECULAR PHARMACOLOGY

Prostaglandin H synthase: Resolved and unresolved mechanistic issues

(2009) Ah-Lim Tsai et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Differential Sensitivity and Mechanism of Inhibition of COX-2 Oxygenation of Arachidonic Acid and 2-Arachidonoylglycerol by Ibuprofen and Mefenamic Acid

(2009) Jeffery J. Prusakiewicz et al.   BIOCHEMISTRY

Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers

(2009) Chong Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1

(2009) G. Rimon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Distinct Pathways for Cyclooxygenase-2 Protein Degradation

(2008) Uri R. Mbonye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclooxygenases: structural and functional insights

(2008) Carol A. Rouzer et al.   JOURNAL OF LIPID RESEARCH

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

Nutritionally essential fatty acids and biologically indispensable cyclooxygenases

(2008) William L. Smith   TRENDS IN BIOCHEMICAL SCIENCES

Quantitation of heme oxygenase 1: Heme titration increases yield of purified protein

(2007) Warren J. Huber et al.   ANALYTICAL BIOCHEMISTRY