Mapping the Catalytic Cycle ofSchistosoma mansoniThioredoxin Glutathione Reductase by X-ray Crystallography

Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths

(2010) Lucía Otero et al.   BMC GENOMICS

Using chemical approaches to study selenoproteins—Focus on thioredoxin reductases

(2009) Robert J. Hondal   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions

(2009) Elias S.J. Arnér   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition ofSchistosoma mansoniThioredoxin-glutathione Reductase by Auranofin

(2009) Francesco Angelucci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against Schistosomiasis

(2009) Ganesha Rai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Control of schistosomiasis in sub-Saharan Africa: progress made, new opportunities and remaining challenges

(2009) J. R. STOTHARD et al.   PARASITOLOGY

Acid−Base Catalysis in the Mechanism of Thioredoxin Reductase fromDrosophila melanogaster†

(2008) Hsin-Hung Huang et al.   BIOCHEMISTRY

Function of Glu-469′ in the Acid−Base Catalysis of Thioredoxin Reductase fromDrosophila melanogaster†

(2008) Hsin-Hung Huang et al.   BIOCHEMISTRY

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Platyhelminth Mitochondrial and Cytosolic Redox Homeostasis Is Controlled by a Single Thioredoxin Glutathione Reductase and Dependent on Selenium and Glutathione

(2008) Mariana Bonilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure and Catalysis of the Selenoprotein Thioredoxin Reductase 1

(2008) Qing Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catalytic Cycle of Human Glutathione Reductase Near 1 Å Resolution

(2008) Donald S. Berkholz et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

(2008) Ahmed A Sayed et al.   NATURE MEDICINE

Glutathione reductase and thioredoxin reductase at the crossroad: The structure of Schistosoma mansoni thioredoxin glutathione reductase

(2008) Francesco Angelucci et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Will new antischistosomal drugs finally emerge?

(2008) Donato Cioli et al.   TRENDS IN PARASITOLOGY