Local Sequence Targeting in the AID/APOBEC Family Differentially Impacts Retroviral Restriction and Antibody Diversification

Determinants of sequence-specificity within human AID and APOBEC3G

(2010) Michael A. Carpenter et al.   DNA REPAIR

Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID

(2010) Meng Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis

(2010) H. A. Sadler et al.   JOURNAL OF VIROLOGY

Human APOBEC3G-Mediated Editing Can Promote HIV-1 Sequence Diversification and Accelerate Adaptation to Selective Pressure

(2010) E.-Y. Kim et al.   JOURNAL OF VIROLOGY

APOBEC3F and APOBEC3G Inhibit HIV-1 DNA Integration by Different Mechanisms

(2010) J. L. Mbisa et al.   JOURNAL OF VIROLOGY

A Portable Hot Spot Recognition Loop Transfers Sequence Preferences from APOBEC Family Members to Activation-induced Cytidine Deaminase

(2009) Rahul M. Kohli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting APOBEC3G Substrate Specificity by Nucleoside Analog Interference

(2009) Jason W. Rausch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunoglobulin switch μ sequence causes RNA polymerase II accumulation and reduces dA hypermutation

(2009) Deepa Rajagopal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Analysis and Structural Modeling of Human APOBEC3G Reveal the Role of Evolutionarily Conserved Elements in the Inhibition of Human Immunodeficiency Virus Type 1 Infection and Alu Transposition

(2009) Y. Bulliard et al.   JOURNAL OF VIROLOGY

AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity

(2009) Meng Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA

(2009) Rebecca A Russell et al.   Retrovirology

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent

(2009) Edward P. Browne et al.   VIROLOGY

RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

(2009) Hendrik Huthoff et al.   PLoS Pathogens

Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

(2008) M.-A. Langlois et al.   JOURNAL OF VIROLOGY

Conserved Footprints of APOBEC3G on Hypermutated Human Immunodeficiency Virus Type 1 and Human Endogenous Retrovirus HERV-K(HML2) Sequences

(2008) A. E. Armitage et al.   JOURNAL OF VIROLOGY

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

(2008) A. J. Schumacher et al.   JOURNAL OF VIROLOGY

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

(2008) Lauren G. Holden et al.   NATURE

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

(2008) Kuan-Ming Chen et al.   NATURE

Cytidine deamination induced HIV-1 drug resistance

(2008) L. C. F. Mulder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation

(2008) H. P. Bogerd et al.   RNA