TopBP1 Deficiency Causes an Early Embryonic Lethality and Induces Cellular Senescence in Primary Cells

Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication

(2010) Akiko Kumagai et al.   CELL

γH2A binds Brc1 to maintain genome integrity during S-phase

(2010) Jessica S Williams et al.   EMBO JOURNAL

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator

(2010) C. L. Sansam et al.   GENES & DEVELOPMENT

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

(2010) Alessia Balestrini et al.   NATURE CELL BIOLOGY

A comparative analysis of the cell biology of senescence and aging

(2009) Eun Seong Hwang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of p53 by TopBP1: a Potential Mechanism for p53 Inactivation in Cancer

(2009) K. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM

(2009) Hae Yong Yoo et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

(2008) Chao Xu et al.   JOURNAL OF MOLECULAR BIOLOGY