Heparanase Plays a Dual Role in Driving Hepatocyte Growth Factor (HGF) Signaling by Enhancing HGF Expression and Activity

The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis

(2011) Weon-Kyoo You et al.   BMB Reports

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis

(2010) A. Purushothaman et al.   BLOOD

Heparanase Enhances Local and Systemic Osteolysis in Multiple Myeloma by Upregulating the Expression and Secretion of RANKL

(2010) Y. Yang et al.   CANCER RESEARCH

Proteoglycans in health and disease: the multiple roles of syndecan shedding

(2010) Tina Manon-Jensen et al.   FEBS Journal

Hepatocyte growth factor activator (HGFA): pathophysiological functions in vivo

(2010) Hiroaki Kataoka et al.   FEBS Journal

Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis

(2010) Uri Barash et al.   FEBS Journal

Mechanism of TNF-α-induced migration and hepatocyte growth factor production in human mesenchymal stem cells

(2010) Aibin Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Targeting the HGF/c-Met Axis: State of Play

(2010) T. A. Yap et al.   MOLECULAR CANCER THERAPEUTICS

Structure-Function Approach Identifies a COOH-Terminal Domain That Mediates Heparanase Signaling

(2009) L. Fux et al.   CANCER RESEARCH

Syndecan-1 Is Required for Robust Growth, Vascularization, and Metastasis of Myeloma Tumorsin Vivo

(2009) Yekaterina B. Khotskaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase: busy at the cell surface

(2009) Liat Fux et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heparanase Stimulation of Protease Expression Implicates It as a Master Regulator of the Aggressive Tumor Phenotype in Myeloma

(2008) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

The biological role of HGF-MET axis in tumor growth and development of metastasis

(2007) Ewa Lesko   Frontiers in Bioscience-Landmark