Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins

Plasmodium falciparum from Pará state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA-type PfATPase6

(2010) Isabel D. Ferreira et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1α and P-glycoprotein overexpression

(2009) C Riganti et al.   BRITISH JOURNAL OF PHARMACOLOGY

Docking Studies of Structurally Diverse Antimalarial Drugs Targeting PfATP6: No Correlation between in silico Binding Affinity and in vitro Antimalarial Activity.

(2009) Fatima Bousejra-El Garah et al.   ChemMedChem

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction

(2009) Luke H. Stockwin et al.   INTERNATIONAL JOURNAL OF CANCER

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthesis, Antimalarial Activity, and Intracellular Targets of MEFAS, a New Hybrid Compound Derived from Mefloquine and Artesunate

(2008) F. de Pilla Varotti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of Artemisinins and Amino Alcohol Partner Antimalarials on Mammalian Sarcoendoplasmic Reticulum Calcium Adenosine Triphosphatase Activity

(2008) Stephen Toovey et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent

(2008) Carmony L. Hartwig et al.   BIOCHEMICAL PHARMACOLOGY

Crystal Structure of D351A and P312A Mutant Forms of the Mammalian Sarcoplasmic Reticulum Ca2+-ATPase Reveals Key Events in Phosphorylation and Ca2+Release

(2008) Alexandre Marchand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China

(2008) Guoqing Zhang et al.   MALARIA JOURNAL

Production, characterization and crystallization of the Plasmodium falciparum aquaporin

(2008) Kristina Hedfalk et al.   PROTEIN EXPRESSION AND PURIFICATION

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE

Recent highlights in antimalarial drug resistance and chemotherapy research

(2008) David A. Fidock et al.   TRENDS IN PARASITOLOGY

Artemisinins: their growing importance in medicine

(2008) Sanjeev Krishna et al.   TRENDS IN PHARMACOLOGICAL SCIENCES