A Novel Ca2+/Calmodulin Antagonist HBC Inhibits Angiogenesis and Down-regulates Hypoxia-inducible Factor

Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: The mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1

(2010) Xin-zhi Huang et al.   CANCER BIOLOGY & THERAPY

Terpestacin Inhibits Tumor Angiogenesis by Targeting UQCRB of Mitochondrial Complex III and Suppressing Hypoxia-induced Reactive Oxygen Species Production and Cellular Oxygen Sensing

(2010) Hye Jin Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marked Activity of Irinotecan and Rapamycin Combination toward Colon Cancer Cells In vivo and In vitro Is Mediated through Cooperative Modulation of the Mammalian Target of Rapamycin/Hypoxia-Inducible Factor-1  Axis

(2009) E. Pencreach et al.   CLINICAL CANCER RESEARCH

Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment

(2009) K. Burkitt et al.   MOLECULAR CANCER THERAPEUTICS

Combination Strategy Targeting the Hypoxia Inducible Factor-1  with Mammalian Target of Rapamycin and Histone Deacetylase Inhibitors

(2008) H. M.W. Verheul et al.   CLINICAL CANCER RESEARCH

Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy

(2008) P García-Maceira et al.   ONCOGENE