Growth and Metastases of Human Lung Cancer Are Inhibited in Mouse Xenografts by a Transition State Analogue of 5′-Methylthioadenosine Phosphorylase

Cancer Chemoprevention Locks onto a New Polyamine Metabolic Target

(2010) E. W. Gerner   Cancer Prevention Research

KRASmutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: Implication for combinatorial approach

(2010) Young-Kwang Yoon et al.   MOLECULAR CARCINOGENESIS

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

Polyamine catabolism and disease

(2009) Robert A. Casero et al.   BIOCHEMICAL JOURNAL

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mice Heterozygous for Germ-line Mutations in Methylthioadenosine Phosphorylase (MTAP) Die Prematurely of T-Cell Lymphoma

(2009) Y. Kadariya et al.   CANCER RESEARCH

Identification and Validation of a Potent Type II Inhibitor of Inactive Polo-like Kinase 1

(2009) Sarah Keppner et al.   ChemMedChem

New TNM classification for non-small-cell lung cancer

(2009) Lynn T Tanoue et al.   Expert Review of Anticancer Therapy

Polyamine biosynthesis impacts cellular folate requirements necessary to maintain S-adenosylmethionine and nucleotide pools

(2009) G. Bistulfi et al.   FASEB JOURNAL

Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry

(2009) Susanne H. Kirsch et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer

(2008) Hedy Lee Kindler et al.   INVESTIGATIONAL NEW DRUGS

Direct and tumor microenvironment mediated influences of 5′-deoxy-5′-(methylthio)adenosine on tumor progression of malignant melanoma

(2008) Axel P. Stevens et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE