Factor VIII Lacking the C2 Domain Retains Cofactor Activityin Vitro

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity

(2009) H. Meems et al.   BLOOD

Cleavage at Arg-1689 Influences Heavy Chain Cleavages during Thrombin-catalyzed Activation of Factor VIII

(2009) Jennifer L. Newell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A phosphatidylserine binding site in factor Va C1 domain regulates both assembly and activity of the prothrombinase complex

(2008) R. Majumder et al.   BLOOD

Generation of enhanced stability factor VIII variants by replacement of charged residues at the A2 domain interface

(2008) H. Wakabayashi et al.   BLOOD

Combining mutations of charged residues at the A2 domain interface enhances factor VIII stability over single point mutations

(2008) H. WAKABAYASHI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

(2008) Jacky Chi Ki Ngo et al.   STRUCTURE