Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells

Insulin-feedback via PI3K-C2α activated PKBα/Akt1 is required for glucose-stimulated insulin secretion

(2010) Barbara Leibiger et al.   FASEB JOURNAL

The direct effects of tacrolimus and cyclosporin A on isolated human islets: A functional, survival and gene expression study

(2010) Marco Bugliani et al.   Islets

Ablation of phosphoinositide-3-kinase class II alpha suppresses hepatoma cell proliferation

(2009) Stanley K.L. Ng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rethinking phosphatidylinositol 3-monophosphate

(2009) Marco Falasca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Insulin Granule Recruitment and Exocytosis Is Dependent on p110  in Insulinoma and Human  -Cells

(2009) G. M. Pigeau et al.   DIABETES

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet  -Cells

(2009) G. da Silva Xavier et al.   DIABETES

Regulation of insulin secretion: a matter of phase control and amplitude modulation

(2009) J. C. Henquin   DIABETOLOGIA

Complex Lipid Requirements for SNARE- and SNARE Chaperone-dependent Membrane Fusion

(2009) Joji Mima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

(2009) J. Mima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of phosphoinositide 3-kinase expression in health and disease

(2009) Klaartje Kok et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pancreatic β-cell mass in European subjects with type 2 diabetes

(2008) J. Rahier et al.   DIABETES OBESITY & METABOLISM

Ca2+-regulated Pool of Phosphatidylinositol-3-phosphate Produced by Phosphatidylinositol 3-Kinase C2α on Neurosecretory Vesicles

(2008) Peter J. Wen et al.   MOLECULAR BIOLOGY OF THE CELL

Down-Regulation of Class II Phosphoinositide 3-Kinase   Expression below a Critical Threshold Induces Apoptotic Cell Death

(2008) W. Elis et al.   MOLECULAR CANCER RESEARCH

Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population

(2007) Makoto Daimon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synaptotagmin VII splice variants α, β, and δ are expressed in pancreatic β-cells and regulate insulin exocytosis

(2007) Benoit R. Gauthier et al.   FASEB JOURNAL

An overview of pancreatic beta-cell defects in human type 2 diabetes: Implications for treatment

(2007) Piero Marchetti et al.   REGULATORY PEPTIDES