NMR and Bioinformatics Discovery of Exosites That Tune Metalloelastase Specificity for Solubilized Elastin and Collagen Triple Helices

Apparent Tradeoff of Higher Activity in MMP-12 for Enhanced Stability and Flexibility in MMP-3

(2010) Xiangyang Liang et al.   BIOPHYSICAL JOURNAL

Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements

(2010) N. L. Fawzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional bases for allosteric control of MMP activities: Can it pave the path for selective inhibition?

(2009) Netta Sela-Passwell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MMP-12 catalytic domain recognizes and cleaves at multiple sites in human skin collagen type I and type III

(2009) Samuel Taddese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Characterisation of the MMP-12-Elastin Adduct

(2009) Ivano Bertini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identification of Specific Hemopexin-like Domain Residues That Facilitate Matrix Metalloproteinase Collagenolytic Activity

(2009) Janelle L. Lauer-Fields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic activation of an allosteric regulatory protein

(2009) Shiou-Ru Tzeng et al.   NATURE

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE

MMP-12 Catalytic Domain Recognizes Triple Helical Peptide Models of Collagen V with Exosites and High Activity

(2008) Rajagopalan Bhaskaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Modulation of Matrix Metalloproteinase 9 (MMP-9) Functions via Exosite Inhibition

(2008) Janelle L. Lauer-Fields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping of macrophage elastase cleavage sites in insoluble human skin elastin

(2008) Samuel Taddese et al.   MATRIX BIOLOGY

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

(2008) Oliver Schilling et al.   NATURE BIOTECHNOLOGY