PDCD10/CCM3 Acts Downstream of γ-Protocadherins to Regulate Neuronal Survival

Clustered protocadherin family

(2010) Takeshi Yagi   DEVELOPMENT GROWTH & DIFFERENTIATION

Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype

(2010) Aubrey C. Chan et al.   FEBS Journal

Recent insights into cerebral cavernous malformations: the molecular genetics of CCM

(2010) Florence Riant et al.   FEBS Journal

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

(2010) M. Fidalgo et al.   JOURNAL OF CELL SCIENCE

CCM3 signaling through sterile 20–like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations

(2010) Xiangjian Zheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Combinatorial homophilic interaction between  -protocadherin multimers greatly expands the molecular diversity of cell adhesion

(2010) D. Schreiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilization of VEGFR2 Signaling by Cerebral Cavernous Malformation 3 Is Critical for Vascular Development

(2010) Y. He et al.   Science Signaling

Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice

(2009) Hong Su et al.   DEVELOPMENTAL BIOLOGY

Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations

(2009) G. Boulday et al.   Disease Models & Mechanisms

Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein

(2009) Katrin Voss et al.   HUMAN MUTATION

Protocadherin-  Family Is Required for Serotonergic Projections to Appropriately Innervate Target Brain Areas

(2009) S. Katori et al.   JOURNAL OF NEUROSCIENCE

Proteomics Analysis Reveals Overlapping Functions of Clustered Protocadherins

(2009) Meng-Hsuan Han et al.   MOLECULAR & CELLULAR PROTEOMICS

CCM2 Mediates Death Signaling by the TrkA Receptor Tyrosine Kinase

(2009) Liraz Harel et al.   NEURON

PiggyBac transgenic strategies in the developing chicken spinal cord

(2009) Yanyan Lu et al.   NUCLEIC ACIDS RESEARCH

A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-  gene cluster

(2008) T. Prasad et al.   DEVELOPMENT

 -Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina

(2008) J. L. Lefebvre et al.   DEVELOPMENT

Inhibition of protocadherin-α function results in neuronal death in the developing zebrafish

(2008) Michelle R. Emond et al.   DEVELOPMENTAL BIOLOGY

ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish

(2008) Benjamin M. Hogan et al.   HUMAN MOLECULAR GENETICS

A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells

(2008) Axel Pagenstecher et al.   HUMAN MOLECULAR GENETICS

α- and γ-Protocadherins Negatively Regulate PYK2

(2008) Jian Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOK1 Translocates from the Golgi to the Nucleus upon Chemical Anoxia and Induces Apoptotic Cell Death

(2008) Emilio Nogueira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The protocadherin-α family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse

(2008) Sonoko Hasegawa et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Gamma-protocadherin homophilic interaction and intracellular trafficking is controlled by the cytoplasmic domain in neurons

(2008) Monica Fernández-Monreal et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

PDCD10, THE GENE MUTATED IN CEREBRAL CAVERNOUS MALFORMATION 3, IS EXPRESSED IN THE NEUROVASCULAR UNIT

(2008) Gamze Tanriover et al.   NEUROSURGERY