Characterization of Celastrol to Inhibit Hsp90 and Cdc37 Interaction

Targeting CDC37: An alternative, kinase-directed strategy for disruption of oncogenic chaperoning

(2011) Jennifer R. Smith et al.   CELL CYCLE

Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90-Cdc37, a Kinome Chaperone-Cochaperone, by Triterpene Celastrol

(2009) Sridhar Sreeramulu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Class of Small Molecule Inhibitors of Hsp90

(2008) Fang Yi et al.   ACS Chemical Biology

Designed TPR Modules as Novel Anticancer Agents

(2008) Aitziber L. Cortajarena et al.   ACS Chemical Biology

Dual Targeting of HSC70 and HSP72 Inhibits HSP90 Function and Induces Tumor-Specific Apoptosis

(2008) Marissa V. Powers et al.   CANCER CELL

Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

(2008) J. L. Holmes et al.   CANCER RESEARCH

Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide- binding Pocket

(2008) Alison Donnelly et al.   CURRENT MEDICINAL CHEMISTRY

The Hsp90 Chaperone Machinery

(2008) Sebastian Karl Wandinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Studies on the Co-chaperone Hop and Its Complexes with Hsp90

(2008) S.C. Onuoha et al.   JOURNAL OF MOLECULAR BIOLOGY

Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule

(2008) Amy Trott et al.   MOLECULAR BIOLOGY OF THE CELL

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

(2008) T. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors

(2008) J R Smith et al.   ONCOGENE

Development and application of Hsp90 inhibitors

(2007) D SOLIT   DRUG DISCOVERY TODAY