Role of Arginine Guanidinium Moiety in Nitric-oxide Synthase Mechanism of Oxygen Activation

Design of Selective Neuronal Nitric Oxide Synthase Inhibitors for the Prevention and Treatment of Neurodegenerative Diseases

(2009) Richard B. Silverman   ACCOUNTS OF CHEMICAL RESEARCH

Fast ferrous heme-NO oxidation in nitric oxide synthases

(2009) Jesús Tejero et al.   FEBS Journal

Tetrahydrobiopterin, superoxide, and vascular dysfunction

(2009) Jeannette Vásquez-Vivar   FREE RADICAL BIOLOGY AND MEDICINE

Crystal Structures of Constitutive Nitric Oxide Synthases in Complex with De Novo Designed Inhibitors†

(2009) Jotaro Igarashi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Peroxynitrite Detoxification and Its Biologic Implications

(2008) Madia Trujillo et al.   ANTIOXIDANTS & REDOX SIGNALING

Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

(2008) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

Revisiting Heme Mechanisms. A Perspective on the Mechanisms of Nitric Oxide Synthase (NOS), Heme Oxygenase (HO), and Cytochrome P450s (CYP450s)

(2008) Yaoqiu Zhu et al.   BIOCHEMISTRY

Catalytic Reduction of a Tetrahydrobiopterin Radical within Nitric-oxide Synthase

(2008) Chin-Chuan Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First Half-Reaction Mechanism of Nitric Oxide Synthase: The Role of Proton and Oxygen Coupled Electron Transfer in the Reaction by Quantum Mechanics/Molecular Mechanics

(2008) Kyung-Bin Cho et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Density Functional Theory Investigation on the Mechanism of the Second Half-Reaction of Nitric Oxide Synthase

(2008) Jesse J. Robinet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Is the Bound Substrate in Nitric Oxide Synthase Protonated or Neutral and What Is the Active Oxidant that Performs Substrate Hydroxylation?

(2008) Sam P. de Visser et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Second Step of the Nitric Oxide Synthase Reaction: Evidence for Ferric-Peroxo as the Active Oxidant

(2008) Joshua J. Woodward et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

(2008) Elsa D Garcin et al.   Nature Chemical Biology