Chemical Validation of Trypanothione Synthetase

Synthesis and Evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) Analogues as Inhibitors of Trypanothione Reductase

(2009) Stephen Patterson et al.   ChemMedChem

Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase inTrypanosoma bruceiusing chemical and genetic methods

(2009) Susan Wyllie et al.   MOLECULAR MICROBIOLOGY

ATP-dependent ligases in trypanothione biosynthesis - kinetics of catalysis and inhibition by phosphinic acid pseudopeptides

(2008) Sandra L. Oza et al.   FEBS Journal

LeishmaniaTrypanothione Synthetase-Amidase Structure Reveals a Basis for Regulation of Conflicting Synthetic and Hydrolytic Activities

(2008) Paul K. Fyfe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetoplastids: related protozoan pathogens, different diseases

(2008) Ken Stuart et al.   JOURNAL OF CLINICAL INVESTIGATION

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology