3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects

Metabolic Targeting of Lactate Efflux by Malignant Glioma Inhibits Invasiveness and Induces Necrosis: An In Vivo Study

(2015) Chaim B Colen et al.   NEOPLASIA

D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate

(2011) S M El Sayed et al.   CANCER GENE THERAPY

Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF- B/IL-8 Pathway that Drives Tumor Angiogenesis

(2011) F. Vegran et al.   CANCER RESEARCH

Targeting glycolysis in leukemia: A novel inhibitor 3-BrOP in combination with rapamycin

(2011) Lauren J. Akers et al.   LEUKEMIA RESEARCH

Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

(2011) E Babu et al.   ONCOGENE

Citric acid treatment of postoperative wound in an operated case of synovial sarcoma of the knee

(2011) Basavraj S Nagoba et al.   International Wound Journal

Bioprocess development of the production of the mutant P-219-L human d-amino acid oxidase for high soluble fraction expression in recombinant Escherichia coli

(2010) Rabab M. Abou El-Magd et al.   BIOCHEMICAL ENGINEERING JOURNAL

IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid

(2010) Masahiko Yabu et al.   INTERNATIONAL IMMUNOLOGY

Potential cytotoxic effect of hydroxypyruvate produced from D-serine by astroglial D-amino acid oxidase

(2010) S. P. Chung et al.   JOURNAL OF BIOCHEMISTRY

Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate

(2009) Muthusamy Thangaraju et al.   CANCER

ABC Transporters, Drug Resistance, and Cancer Stem Cells

(2009) Michael Dean   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia

(2009) RM Abou El-Magd et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Hypothesis proved…citric acid (citrate) does improve cancer: A case of a patient suffering from medullary thyroid cancer

(2009) Alberto Halabe Bucay   MEDICAL HYPOTHESES

Targets of 3-Bromopyruvate, A New, Energy Depleting, Anticancer Agent

(2009) P. Dell'Antone   Medicinal Chemistry

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate1

(2008) Ana Paula Pereira Da Silva et al.   BIOCHEMICAL JOURNAL

Increased levels of superoxide and H2O2mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

(2008) Nùkhet Aykin-Burns et al.   BIOCHEMICAL JOURNAL

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells

(2008) E. Hulleman et al.   BLOOD

Merlin Is a Potent Inhibitor of Glioma Growth

(2008) Y.-K. I. Lau et al.   CANCER RESEARCH

3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs

(2008) Linda Strandberg Ihrlund et al.   Molecular Oncology