Calcineurin-NFAT activation and DSCR-1 auto-inhibitory loop: how is homoeostasis regulated?

A major role for RCAN1 in atherosclerosis progression

(2013) Nerea Méndez-Barbero et al.   EMBO Molecular Medicine

The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium Is Critical for the Establishment of Lung Metastases

(2013) Takashi Minami et al.   Cell Reports

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory

(2012) Katherine R. Martin et al.   HUMAN MOLECULAR GENETICS

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways

(2011) Taiga Tamiya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of RCAN1 Protein Activity by Dyrk1A Protein-mediated Phosphorylation

(2011) Min-Su Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulator of calcineurin 1 mediates pathological vascular wall remodeling

(2011) Vanesa Esteban et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

(2011) S. Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of DYRK1A in neurodegenerative diseases

(2010) Jerzy Wegiel et al.   FEBS Journal

Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

(2010) Louise E. Reynolds et al.   NATURE

Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3

(2009) J.-i. Suehiro et al.   BLOOD

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

(2009) Kwan-Hyuck Baek et al.   NATURE

Targeted Deletion of the Calcineurin Inhibitor DSCR1 Suppresses Tumor Growth

(2008) Sandra Ryeom et al.   CANCER CELL

Transcription Enhancer Factor 3 (TEF3) Mediates the Expression of Down Syndrome Candidate Region 1 Isoform 1 (DSCR1-1L) in Endothelial Cells

(2008) Xin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated levels of placental growth factor represent an adaptive host response in sepsis

(2008) Kiichiro Yano et al.   JOURNAL OF EXPERIMENTAL MEDICINE