An anticancer agent, pyrvinium pamoate inhibits the NADH–fumarate reductase system—a unique mitochondrial energy metabolism in tumour microenvironments

Hypoglycemic/hypoxic condition in vitro mimicking the tumor microenvironment markedly reduced the efficacy of anticancer drugs

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Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

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Revisiting the TCA cycle: signaling to tumor formation

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The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments

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Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin

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Regulation of Cellular Metabolism by Protein Lysine Acetylation

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Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

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Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose Deprivation

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Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

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Regulation of succinate-ubiquinone reductase and fumarate reductase activities in human complex II by phosphorylation of its flavoprotein subunit

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Non-competitive androgen receptor inhibition in vitro and in vivo

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy of Pyrvinium Pamoate against Cryptosporidium parvum Infection In Vitro and in a Neonatal Mouse Model

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Autophagy and cancer: Dynamism of the metabolism of tumor cells and tissues

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover

(2008) Carsten Denkert et al.   Molecular Cancer

Pyrvinium Targets the Unfolded Protein Response to Hypoglycemia and Its Anti-Tumor Activity Is Enhanced by Combination Therapy

(2008) De-Hua Yu et al.   PLoS One

Change of subunit composition of mitochondrial complex II (succinate–ubiquinone reductase/quinol–fumarate reductase) in Ascaris suum during the migration in the experimental host

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