Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development

5-Hydroxyindole-2-carboxylic Acid Amides: Novel Histamine-3 Receptor Inverse Agonists for the Treatment of Obesity

(2009) Pascale David Pierson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

(2008) Kun L. Ma et al.   HEPATOLOGY

LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney

(2008) Kenneth R. Feingold et al.   JOURNAL OF LIPID RESEARCH

Gene expression profiling of methapyrilene-induced hepatotoxicity in rat

(2008) Takeki Uehara et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Safety evaluation to support first-in-man investigations II: Toxicology studies

(2008) Paul Baldrick   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity

(2008) M ELFERINK et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Commentary: Regulatory Toxicology and the Critical Path: Predicting Long-term Outcomes from Short-term Studies

(2008) D. Jacobson-Kram   VETERINARY PATHOLOGY