4.4 Article

The Proteome and Interactome of Streptococcus pneumoniae Phage Cp-1

Journal

JOURNAL OF BACTERIOLOGY
Volume 193, Issue 12, Pages 3135-3138

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01481-10

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Funding

  1. Landesstiftung Baden-Wurttemberg of Germany
  2. Karlsruhe House of Young Scientists
  3. J. Craig Venter Institute
  4. Canadian Institutes of Health Research
  5. European Union [HEALTH-F3-2009-223101]

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Mass spectrometry analysis of Streptococcus pneumoniae bacteriophage Cp-1 identified a total of 12 proteins, and proteome-wide yeast two-hybrid screens revealed 17 binary interactions mainly among these structural proteins. On the basis of the resulting linkage map, we suggest an improved structural model of the Cp-1 virion.

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