Article
Orthopedics
Alfred P. Yoon, William T. Chung, Chien-Wei Wang, Chang-Fu Kuo, Chihung Lin, Kevin C. Chung
Summary: Using CNN assistance improves interobserver agreement and diagnostic sensitivity and specificity for occult scaphoid fractures. However, there is no clinically significant difference observed in diagnostic speed and confidence levels between CNN-assisted and non-assisted image interpretation.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2023)
Article
Psychiatry
Jie Luo, Huanhuan Huang, Shuang Wang, Shengjian Yin, Sijian Chen, Lin Guan, Xinlong Jiang, Fan He, Yi Zheng
Summary: This study designed a diagnostic test to assess the effectiveness and accuracy of A non-intrusive Wearable Diagnostic Assessment System compared to SNAP-IV for auxiliary diagnosis of children with ADHD. The results showed that the WeDA system had higher sensitivity, specificity, and diagnostic efficacy compared to SNAP-IV.
Article
Clinical Neurology
Yaira Chamorro, Lourdes Bolanos, Salvador Trejo, Omar Barrios, Maria de Lourdes Ramirez-Duenas, Pablo Alvarez-Tostado, Alan Cervantes, Esmeralda Matute
Summary: The study found low agreement between parents and teachers when rating ADHD symptoms, especially in higher grades. Boys were more likely to be diagnosed as meeting ADHD criteria, but agreement by sex was low.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
James Thomas Patrick Decourcy Hallinan, Lei Zhu, Kaiyuan Yang, Andrew Makmur, Diyaa Abdul Rauf Algazwi, Yee Liang Thian, Samuel Lau, Yun Song Choo, Sterling Ellis Eide, Qai Ven Yap, Yiong Huak Chan, Jiong Hao Tan, Naresh Kumar, Beng Chin Ooi, Hiroshi Yoshioka, Swee Tian Quek
Summary: This study aimed to develop a deep learning model for automated detection and classification of lumbar central canal, lateral recess, and neural foraminal stenosis on MRI. The results showed that the deep learning model demonstrated comparable agreement with subspecialist radiologists for the detection and classification of central canal and lateral recess stenosis, with slightly lower agreement for neural foraminal stenosis.
Article
Hematology
Ivan Civettini, Arianna Zappaterra, Bianca Maria Granelli, Giovanni Rindone, Andrea Aroldi, Stefano Bonfanti, Federica Colombo, Marilena Fedele, Giovanni Grillo, Matteo Parma, Paola Perfetti, Elisabetta Terruzzi, Carlo Gambacorti-Passerini, Daniele Ramazzotti, Fabrizio Cavalca
Summary: This study assessed the capabilities of large language models in making complex decisions in haematopoietic stem cell transplantation and found that residents outperformed the models. The study revealed both the promise and limitations of language models in deciphering complex haematological clinical scenarios.
BRITISH JOURNAL OF HAEMATOLOGY
(2023)
Article
Psychology, Developmental
Patricia Silva Lucio, Michael Eid, Hugo Cogo-Moreira, Marina Leite Puglisi, Guilherme Polanczyk
Summary: The study aimed to validate the trait structure and gender differences of SNAP-IV in preschool children, and investigate the impact of different raters on ADHD/ODD assessments.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2022)
Article
Psychiatry
Xia Huang, Hui-Qin Li, Alan Simpson, Jia-Jun Xu, Wan-Jie Tang, Yuan-Yuan Li
Summary: This study aimed to understand the differences in scores among fathers, mothers, and teachers when using the SNAP-IV scale and explore the differences in scoring results under different scoring methods. The results showed differences in scores among the three groups, and the differences showed inconsistent trends across different subscales. The familiarity of parents and teachers with the patients did not affect the differences in their scores, and comprehensive considerations should be made from both the scorer and symptom dimensions.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Biology
David G. Pina, Ivan Buljan, Darko Hren, Ana Marusic
Summary: Research indicates that changes in the organization of peer review for proposals submitted to the European Union's Marie Curie programme had little impact on the outcome, with factors such as grant type or research area playing a more significant role.
Article
Behavioral Sciences
Diangang Fang, Binrang Yang, Peng Wang, Tong Mo, Yungen Gan, Guohua Liang, Rong Huang, Hongwu Zeng
Summary: This study investigated the role and underlying mechanism of the SNAP-25 MnlI variant in cognitive impairment and brain functions in boys with ADHD. The results showed that TT homozygotes had higher WM capacity and ReHo values for the left mPFC compared to G-allele carriers. However, the WM capacity in the G-allele carrier group was negatively correlated with the peak ReHo value for the left mPFC.
BRAIN AND BEHAVIOR
(2022)
Article
Psychiatry
Hasanthi C. Abhayaratna, Dewasmika I. Ariyasinghe, Pabasari Ginige, Miyuru Chandradasa, K. Supuni Hansika, Anshu Fernando, Swarna Wijetunge, Tharaka L. Dassanayake
Summary: The objective of this study was to translate and adapt the SNAP-IV Parent Form into Sinhala language and evaluate its psychometric properties. The Sinhala version of SNAP-IV (S-SNAP-IV) showed a three-factor structure and excellent internal consistency in both healthy and clinical samples. It also demonstrated good discriminative validity in distinguishing children with ADHD from non-ADHD children. The S-SNAP-IV is considered a reliable and valid instrument for screening children with ADHD.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Endocrinology & Metabolism
Alessia Valente, Jacopo Mariani, Serena Seminara, Mauro Tettamanti, Giuseppe Pignataro, Carlo Perego, Luigi Sironi, Felicita Pedata, Diana Amantea, Marco Bacigaluppi, Antonio Vinciguerra, Susanna Diamanti, Martina Vigano, Francesco Santangelo, Chiara Paola Zoia, Virginia Rodriguez-Menendez, Laura Castiglioni, Joanna Rzemieniec, Ilaria Dettori, Irene Bulli, Elisabetta Coppi, Chiara Di Santo, Ornella Cuomo, Giorgia Serena Gullotta, Erica Butti, Giacinto Bagetta, Gianvito Martino, Maria-Grazia De Simoni, Carlo Ferrarese, Stefano Fumagalli, Simone Beretta
Summary: Multicentre preclinical randomized controlled trials (pRCTs) are a valuable tool to improve experimental stroke research, but the standardization of procedures across centres is challenging. This study demonstrates that a multi-step, online harmonization phase is feasible and effective in aligning behavioural evaluations before the interventional phase of the project, resulting in satisfactory interrater agreement.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Article
Psychology, Multidisciplinary
Alexis Federico, Dexin Shi, Jessica Bradshaw
Summary: This study investigated the association between parent report and clinician observation measures of social communication and motor skills in young infants at 9 and 12 months of age. The results showed a strong relation between clinician and parent rated motor skills, but weak to moderate associations between clinician and parent rated communication skills. Infant temperament played a significant role in parent ratings of infant communication.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Mathematical
Michael Kevane, Birgit Koopmann-Holm
Summary: This paper examines the reliability and validity of classification images of faces using the reverse correlation approach, focusing on trial order effects, compliance, and reliability effects, as well as the degree of contextual contrast of image pairs. Through analysis of data from 12 studies, the study presents solutions and methods for these issues, providing R scripts for easy implementation in related research.
BEHAVIOR RESEARCH METHODS
(2021)
Article
Cardiac & Cardiovascular Systems
Hythem Nawaytou, Christine Springston, Ann Lazar, Samuel Keller, Whitnee Hogan, Nicole Cresalia, Shabnam Peyvandi, Mark Cocalis, Anita Moon-Grady, Michael Brook
Summary: Implementing a measurement-based protocol can improve the interrater agreement and accuracy of RV systolic pressure assessment in children. Reliable measurements (RV systolic pressure and dilation) resulted in improved agreement, while unreliable measurements (RV hypertrophy and systolic function) did not.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2022)
Article
Economics
Edna Keeney, Howard Thom, Emma Turner, Richard M. Martin, Sabina Sanghera
Summary: This study utilized a modified Delphi approach to address decision-question uncertainty, identifying relevant prostate cancer screening strategies through two rounds of online questionnaires with international researchers, clinicians, and decision makers. Consensus was found towards comparing no formal screening, age-based, and risk-based strategies, but there was disagreement on the inclusion of new biomarkers.
Article
Psychology, Developmental
Aline Romani-Sponchiado, Pablo Vidal-Ribas, Rodrigo Affonseca Bressan, Jair de Jesus Mari, Euripedes Constantino Miguel, Ary Gadelha, Luis Augusto Paim Rohde, Sara Evans-Lacko, Giovanni Abrahao Salum, Mauricio Scopel Hoffmann
Summary: Psychopathology and positive attributes mutually influence each other over the long term and have interactive effects on educational outcomes.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Carolina Ziebold, Sara Evans-Lacko, Mario Cesar Rezende Andrade, Mauricio Hoffmann, Lais Fonseca, Matheus Barbosa, Pedro Mario Pan, Euripedes Miguel, Rodrigo Bressan, Luis Augusto Rohde, Giovanni Salum, Julia Schafer, Jair de Jesus Mari, Ary Gadelha
Summary: This study explored the association between childhood poverty and mental health disorders in childhood and early adulthood. It found that poverty had a significant impact on the occurrence of externalizing disorders in adolescence, especially among females. Childhood poverty increased the likelihood of externalizing disorders in early adulthood through exposure to stressful life events.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Betina Soldateli, Rita C. Silveira, Renato Soibelmann Procianoy, Mandy Belfort, Arthur Caye, Douglas Leffa, Adelar Pedro Franz, Fernando C. Barros, Ina S. Santos, Alicia Matijasevich, Aluisio J. D. Barros, Luciana Tovo-Rodrigues, Ana M. B. Menezes, Helen Goncalves, Fernando C. Wehrmeister, Luis Augusto Paim Rohde
Summary: The objective of this study is to examine the association between preterm infants' size at 1 year and attention-deficit/hyperactivity disorder (ADHD) assessed in childhood and adolescence. The findings suggest that increased head circumference at 1 year is associated with a lower risk of ADHD diagnosis and fewer attention symptoms.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Luiza K. Axelrud, Mauricio S. Hoffmann, Daniel E. Vosberg, Marcos Santoro, Pedro M. Pan, Ary Gadelha, Sintia Belangero, Euripedes C. Miguel, Jean Shin, Anita Thapar, Jordan W. Smoller, Zdenka Pausova, Luis A. Rohde, Matthew C. Keller, Tomas Paus, Giovanni A. Salum
Summary: This study aimed to investigate the influence of parental genetics on offspring cognition, educational attainment, and psychopathology. The findings suggest that parental genetics influence offspring outcomes through genetic and phenotypic pathways, and multiple mediations may be an effective approach for understanding intergenerational transmission of behavioral traits.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Review
Psychology, Developmental
Edmund J. S. Sonuga-Barke, Stephen P. Becker, Sven Bolte, Francisco Xavier Castellanos, Barbara Franke, Jeffrey H. Newcorn, Joel T. Nigg, Luis Augusto Rohde, Emily Simonoff
Summary: The article provides a comprehensive overview of the scientific field of ADHD, covering clinical characteristics, risk factors, causal processes, and neurobiological pathways. The authors also discuss the future of the ADHD construct in light of recent conceptual reformulations.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Psychiatry
Mauricio Scopel Hoffmann, Tyler Maxwell Moore, Luiza Kvitko Axelrud, Nim Tottenham, Luis Augusto Rohde, Michael Peter Milham, Theodore Daniel Satterthwaite, Giovanni Abrahao Salum
Summary: The study provides a method to harmonize mental health data using different bifactor model configurations. The analysis shows that only a few model configurations are reliable and instrument-invariant in harmonizing psychopathology instruments.
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Douglas T. Leffa, Joao Pedro Ferrari-Souza, Bruna Bellaver, Cecile Tissot, Pamela C. L. Ferreira, Wagner S. Brum, Arthur Caye, Jodie Lord, Petroula Proitsi, Thais Martins-Silva, Luciana Tovo-Rodrigues, Dana L. Tudorascu, Victor L. Villemagne, Ann D. Cohen, Oscar L. Lopez, William E. Klunk, Thomas K. Karikari, Pedro Rosa-Neto, Eduardo R. Zimmer, Brooke S. G. Molina, Luis Augusto Rohde, Tharick A. Pascoal
Summary: The genetic liability for attention-deficit/hyperactivity disorder (ADHD) is associated with cognitive decline and the development of Alzheimer's Disease (AD) pathology, especially in individuals with increased amyloid-beta (Aβ) deposition.
MOLECULAR PSYCHIATRY
(2023)
Article
Genetics & Heredity
Ditte Demontis, G. Bragi Walters, Georgios Athanasiadis, Raymond Walters, Karen Therrien, Trine Tollerup Nielsen, Leila Farajzadeh, Georgios Voloudakis, Jaroslav Bendl, Biau Zeng, Wen Zhang, Jakob Grove, Thomas D. Als, Jinjie Duan, F. Kyle Satterstrom, Jonas Bybjerg-Grauholm, Marie Baekved-Hansen, Olafur O. Gudmundsson, Sigurdur H. Magnusson, Gisli Baldursson, Katrin Davidsdottir, Gyda S. Haraldsdottir, Esben Agerbo, Gabriel E. Hoffman, Soren Dalsgaard, Joanna Martin, Marta Ribases, Dorret Boomsma, Maria Soler Artigas, Nina Roth Mota, Daniel Howrigan, Sarah E. Medland, Tetyana Zayats, Veera M. Rajagopal, Merete Nordentoft, Ole Mors, David M. Hougaard, Preben Bo Mortensen, Mark J. Daly, Stephen Faraone, Hreinn Stefansson, Panos Roussos, Barbara Franke, Thomas Werge, Benjamin M. Neale, Kari Stefansson, Anders D. Borglum
Summary: This study conducted a meta-analysis of genome-wide association studies on ADHD and identified 27 significant genetic loci associated with ADHD. They also found that these loci were enriched with genes involved in early brain development. Moreover, they discovered an increased load of rare protein-truncating variants in ADHD, implicating SORCS3 as a potential gene involved in ADHD.
Article
Psychiatry
Luiz Roberto Carvalho, Leticia M. Haas, Gregory Zeni, Marcelo M. Victor, Stefania P. Techele, Julia Marrone Castanho, Isabel Meneghetti Coimbra, Anthony de Freitas de Sousa, Nathalia Ceretta, Alia Garrudo, Eugenio Horacio Grevet, Luis Augusto Rohde
Summary: This study evaluated the performance of the FOCUS ADHD mobile health application in improving medication adherence and ADHD knowledge among patients. The addition of a financial incentive for using the app resulted in higher medication intake registrations. However, app use did not increase ADHD knowledge. Overall, the FOCUS ADHD app received high adoption and positive evaluations from users.
EUROPEAN PSYCHIATRY
(2023)
Article
Behavioral Sciences
Joao Ricardo Sato, Claudinei Eduardo Biazoli, Ana Paula Arantes Bueno, Arthur Caye, Pedro Mario Pan, Marcos Santoro, Jessica Honorato-Mauer, Giovanni Abrahao Salum, Marcelo Queiroz Hoexter, Rodrigo Affonseca Bressan, Andrea Parolin Jackowski, Euripedes Constantino Miguel, Sintia Belangero, Luis Augusto Rohde
Summary: Neuroimaging studies suggest that brain development mechanisms may explain some ADHD symptoms. However, the mechanisms by which genetic factors influence brain development in relation to ADHD remain largely unknown. This study aimed to investigate the associations between an ADHD polygenic risk score and brain network functioning. The findings suggest correlations between the ADHD polygenic risk score and the segregation of cingulo-opercular networks and the default mode network, supporting the role of attentional networks and DMN in attention processes. However, these associations were not found at follow-up.
GENES BRAIN AND BEHAVIOR
(2023)
Article
Psychology, Developmental
Marcelo Moraes Victor, Leticia Mueller Haas, Eugenio Horacio Grevet, Luis Augusto Rohde
Summary: This report presents a case of attentional symptoms and fatigue that emerged after SARS-CoV-2 infection. The patient achieved remission of his symptoms through several changes in the therapeutic regimen. This case highlights the importance of treating PCS inattention and fatigue as an ADHD-like syndrome.
JOURNAL OF ATTENTION DISORDERS
(2023)
Article
Clinical Neurology
Maria Eduarda de Araujo Tavares, Renata Basso Cupertino, Cibele Edom Bandeira, Bruna Santos da Silva, Eduardo Schneider Vitola, Carlos Alberto Iglesias Salgado, Robson dos Santos Soares, Felipe Almeida Picon, Luis Augusto Rohde, Diego Luiz Rovaris, Eugenio Horacio Grevet, Claiton Henrique Dotto Bau
Summary: GWAS studies have found associations between the MEF2C gene and white matter microstructure as well as psychiatric disorders. Our study in a Brazilian population further supports these findings and suggests a common biological factor underlying these phenotypes. Specifically, we identified independent variants in the MEF2C gene associated with temporal-frontal circuitry, which is relevant to executive and cognitive functions.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Article
Psychiatry
Thiago Henrique Roza, Francisco Diego Rabelo-da-Ponte, Daniel Tornaim Spritzer, Mauricio Scopel Hoffmann, Raffael Massuda, Giovanni Abrahao Salum, Euripedes Constantino Miguel, Luis Augusto Rohde, Pedro Mario Pan, Felix Henrique Paim Kessler, Ary Gadelha, Ives Cavalcante Passos
Summary: This study aimed to investigate the relationship between maternal depression in childhood and problematic gaming in late adolescence/young adulthood. Data from a large Brazilian school-based cohort were collected and analyzed, and it was found that maternal depression in childhood was significantly associated with problematic gaming in later developmental stages, partially mediated by internalizing psychopathology.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Correction
Genetics & Heredity
Ditte Demontis, G. Bragi Walters, Georgios Athanasiadis, Raymond Walters, Karen Therrien, Trine Tollerup Nielsen, Leila Farajzadeh, Georgios Voloudakis, Jaroslav Bendl, Biau Zeng, Wen Zhang, Jakob Grove, Thomas D. Als, Jinjie Duan, F. Kyle Satterstrom, Jonas Bybjerg-Grauholm, Marie H. Baekved-Hansen, Olafur Gudmundsson, Sigurdur Magnusson, Gisli Baldursson, Katrin C. Davidsdottir, Gyda Haraldsdottir, Esben Agerbo, Gabriel M. Hoffman, Soren Dalsgaard, Jonna Martin, Marta Ribases, Dorret H. Boomsma, Maria Soler Artigas, Nina Roth Mota, Daniel Howrigan, Sarah J. Medland, Tetyana J. Zayats, Veera Rajagopal, Merete Nordentoft, Ole Mors, David M. Hougaard, Preben Bo Mortensen, Mark J. Daly, Stephen V. Faraone, Hreinn Stefansson, Panos Roussos, Barbara Franke, Thomas Werge, Benjamin M. Neale, Kari Stefansson, Anders D. Borglum
Article
Psychiatry
Matheus Ghossain Barbosa, Viviane Machado, Carolina Ziebold, Tais Moriyama, Rodrigo A. Bressan, Pedro Pan, Luis Augusto Rohde, Euripedes Constantino Miguel, Lais Fonseca, Jim Van Os, Ary Gadelha
Summary: The Brazilian High-Risk Cohort study examined the measurement invariance of the CAPE-positive scale in children and adolescents over a three-year period. The results show that the scale is not invariant over time, indicating the need for further investigation into the factors influencing its results.
SCHIZOPHRENIA RESEARCH
(2023)
