Review
Pharmacology & Pharmacy
Kong Yen Liew, Nurain Irdayani Kamise, Hui Ming Ong, Poi Yi Aw Yong, Fahmida Islam, Ji Wei Tan, Chau Ling Tham
Summary: Allergic diseases are a global health burden, and the current available medications have side effects, poor perceived effectiveness, and high cost. Propolis, a natural herbal medicine with antioxidant, antimicrobial, and anticancer properties, has the potential to be a prophylactic or therapeutic option for allergic diseases. Preclinical studies have shown that propolis extracts have therapeutic effects on allergic inflammation, asthma, allergic rhinitis, atopic dermatitis, and food allergy by inhibiting mast cell and basophil activation. Clinically, propolis consumption as a supplement or adjunct therapy is safe and attenuates pathological conditions in asthma. Flavonoids and cinnamic acid derivatives in propolis contribute to its anti-allergic activities, but their presence varies in different propolis samples. Future studies should focus on the relationship between propolis's anti-allergic activity and its chemical contents.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Mohammed A. Alfurayh, Mouath A. Alturaymi, Ahmed Sharahili, Majed A. Bin Dayel, Abdullah Al Eissa, Muath O. Alilaj
Summary: Severe uncontrolled asthma in the pediatric population is a major challenge for pediatricians, as it is related to significant morbidity and mortality. Children with complicated asthma are at a higher risk for unfavorable outcomes, including medication-associated adverse effects, severe life-threatening exacerbations, and poor quality of life.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Christina Pirner, Christine Korbely, Stefanie Heinze, Jonas Huss, Burkhard Summer, Eva Oppel, Dennis Nowak, Caroline Herr, Susanne Kutzora
Summary: A study on the time trend of prevalence of atopic diseases and airway-related symptoms among Bavarian children before starting primary school found that while some diseases showed a stagnation in prevalence, others exhibited a decreasing or increasing trend over the years.
RESPIRATORY MEDICINE
(2022)
Article
Clinical Neurology
Hee-Kyung Joh, Hyuktae Kwon, Ki Young Son, Jae Moon Yun, Su Hwan Cho, Kyungdo Han, Jin-Ho Park, Belong Cho
Summary: This study examines the association between the allergic triad (asthma, allergic rhinitis, atopic dermatitis) and the risk of dementia. The results indicate that allergic diseases are positively associated with dementia risk, and the severity of allergic diseases has a dose-effect relationship with dementia risk.
ANNALS OF NEUROLOGY
(2023)
Article
Allergy
Hui Gan, Zhifeng Huang, Huiqing Zhu, Aoli Li, Tong Chen, Ziyu Yin, Baoqing Sun
Summary: This study found a positive correlation between allergies of children and their parents. Maternal allergies or sensitization did not significantly affect children's symptoms or quality-of-life scores, while paternal allergies affected children's quality of life but not their rhinitis symptoms.
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
(2023)
Article
Environmental Sciences
Wenxin Lu, Laura Ann Wang, Jennifer Mann, Alisa Jenny, Carolina Romero, Andrea Kuster, Eduardo Canuz, Ajay Pillarisetti, Kirk R. Smith, John Balmes, Lisa Thompson
Summary: Women and children in rural regions of low-income countries are exposed to high levels of household air pollution (HAP) due to their involvement in household chores. Early life exposure to air pollution is associated with aeroallergen sensitization and the development of allergic diseases at older ages. Reducing HAP by improving biomass burning conditions might be beneficial in preventing allergic diseases among children in rural low-income populations.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Yajia Li, Danrong Jing, Yuzhou Huang, Juan Su, Jie Li, Ji Li, Juan Tao, Shijun Shan, Xiaohui Wang, Xiaojing Kang, Bin Wu, Xiang Chen, Minxue Shen, Yi Xiao
Summary: Preschool upper respiratory tract infections and antibiotic use significantly increase the risk of atopic and allergic skin diseases in young adulthood.
Review
Immunology
Chao Luo, Shunlin Peng, Mao Li, Xudong Ao, Zhiqing Liu
Summary: Probiotic supplements are effective in relieving symptoms of allergic rhinitis and improving the quality of life, but there is high heterogeneity in some results.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Allergy
Emma Puosi, Laura S. Korhonen, Linnea Karlsson, Eeva-Leena Kataja, Heikki Lukkarinen, Hasse Karlsson, Minna Lukkarinen
Summary: Maternal chronic depressive and anxiety symptoms during pregnancy are associated with an increased risk of wheezing and eczema in children at 24 months. The study suggests a potential intrauterine programming effect of maternal psychological distress on offspring respiratory health.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Review
Food Science & Technology
Hanieh Malmir, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This meta-analysis found that maternal fish consumption during pregnancy is associated with a lower risk of wheeze, eczema, and food allergy in children. However, there is no significant association between maternal fish consumption and the risk of offspring's asthma, allergic rhinitis, and inhalant allergy.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Allergy
Jan Hagemann, Gabrielle L. Onorato, Marek Jutel, Cezmi A. Akdis, Ioana Agache, Torsten Zuberbier, Wienczyslawa Czarlewski, Joaquim Mullol, Anna Bedbrook, Claus Bachert, Kazi S. Bennoor, Karl-Christian Bergmann, Fulvio Braido, Paulo Camargos, Luis Caraballo, Victoria Cardona, Thomas Casale, Lorenzo Cecchi, Tomas Chivato, Derek K. Chu, Cemal Cingi, Jaime Correia-de-Sousa, Stefano del Giacco, Dejan Dokic, Mark Dykewicz, Motohiro Ebisawa, Yehia El-Gamal, Regina Emuzyte, Jean-Luc Fauquert, Alessandro Fiocchi, Wytske J. Fokkens, Joao A. Fonseca, Bilun Gemicioglu, Rene-Maximiliano Gomez, Maia Gotua, Tari Haahtela, Eckard Hamelmann, Tomohisa Iinuma, Juan Carlos Ivancevich, Ewa Jassem, Omer Kalayci, Przemyslaw Kardas, Musa Khaitov, Piotr Kuna, Violeta Kvedariene, Desiree E. Larenas-Linnemann, Brian Lipworth, Michael Makris, Jorge F. Maspero, Neven Miculinic, Florin Mihaltan, Yousser Mohammad, Stephen Montefort, Mario Morais-Almeida, Ralph Moesges, Robert Naclerio, Hugo Neffen, Marek Niedoszytko, Robyn E. O'Hehir, Ken Ohta, Yoshitaka Okamoto, Kimi Okubo, Petr Panzner, Nikolaos G. Papadopoulos, Giovanni Passalacqua, Vincenzo Patella, Ana Pereira, Oliver Pfaar, Davor Plavec, Todor A. Popov, Emmanuel P. Prokopakis, Francesca Puggioni, Filip Raciborski, Jere Reijula, Frederico S. Regateiro, Sietze Reitsma, Antonino Romano, Nelson Rosario, Menachem Rottem, Dermot Ryan, Boleslaw Samolinski, Joaquin Sastre, Dirceu Sole, Milan Sova, Cristiana Stellato, Charlotte Suppli-Ulrik, Ioanna Tsiligianni, Antonio Valero, Arunas Valiulis, Erkka Valovirta, Tuula Vasankari, Maria Teresa Ventura, Dana Wallace, De Yun Wang, Sian Williams, Arzu Yorgancioglu, Osman M. Yusuf, Mario Zernotti, Jean Bousquet, Ludger Klimek
Summary: By using a modified Delphi approach, upper respiratory symptoms between COVID-19, the common cold, and allergic rhinitis were successfully differentiated, laying the foundation for further research.
Review
Biochemistry & Molecular Biology
Eva Ganseman, Mieke Gouwy, Dominique M. A. Bullens, Christine Breynaert, Rik Schrijvers, Paul Proost
Summary: A significant proportion of adult-onset asthma is caused by occupational exposure to various agents. Insect allergies can occur in several professions, with respiratory symptoms such as asthma being the most common. The recent approval of insects for human consumption by the European Union may increase the risk of occupational insect allergies. This review highlights the need for better diagnostics and primary prevention measures to protect workers in the developing insect industry.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Allergy
Tilo Biedermann, Peter Couroux, Tina Maria Greve, Mika Makela
Summary: The SQ tree SLIT-tablet (12 SQ-Bet) was well tolerated in tree pollen allergic subjects with commonly reported adverse events of oral pruritus and throat irritation, mainly mild to moderate and not leading to treatment interruption. The use of 12 SQ-Bet did not increase the risk of asthma, and there were no differences in the risk of moderate-to-severe adverse events related to age, PFS status, and asthma medical history.
Article
Public, Environmental & Occupational Health
Weiliang Kong, Yilian Xie, Jingjing Zhong, Chao Cao
Summary: This study further supports the association between ultra-processed foods (UPFs) and IgE levels, current asthma in children, and eczema in girls. No association between UPFs and allergic symptoms was observed in adults.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Sarah Preis, Lea Schmidt, Linda Tizek, Maximilian Schielein, Viktoria Lang, Rachela Bleuel, Anna Duswald, Sebastian Sitaru, Annette Blasini, Christine Gasteiger, Lennard Merdha, Zsuzsanna Kurgyis, Bettina Kuschel, Evelyn Hauenstein, Maximilian Sander, Sebastian Niedermeier, Desiree Argiriu, Sabrina Engel, Yuliya Skabytska, Rafaela L. Silva, Miriam Hils, Beatrix Evers, Susanne Kaesler, Hanna Hufnagel, Martin Koeberle, Yacine Amar, Alexander Zink, Tilo Biedermann
Summary: This study aims to comprehensively evaluate the relationship between environmental determinants and the risk of developing atopic dermatitis (AD) in the first four years of a child's life, including individual microbiome and immune responses. Through clinical research and biochemical analysis, the researchers hope to identify different risk factors for AD onset and exacerbation, as well as relevant biomarkers.
