Article
Health Care Sciences & Services
Antonio Espuela-Ortiz, Esther Herrera-Luis, Fabian Lorenzo-Diaz, Donglei Hu, Celeste Eng, Jesus Villar, Jose R. Rodriguez-Santana, Esteban G. Burchard, Maria Pino-Yanes
Summary: This study assessed the influence of sex on genetic susceptibility to childhood asthma in admixed populations. The research identified sex-specific polymorphisms that may contribute to the differences in asthma prevalence between males and females, with the 17q12-21 asthma locus showing higher susceptibility in females and genetic variants upstream of LCORL associated with asthma only in males.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Geriatrics & Gerontology
Michelle C. Odden, Kendra D. Sims, Roland J. Thorpe, Mario Sims, Mandip Dhamoon, Yuan- Min, Adolfo Correa
Summary: This study revealed that half of incident mobility limitations among middle-aged African Americans were transient, with adverse sociodemographic factors and comorbidities associated with lower likelihood of recovery.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Oncology
Carl S. Winkler, John C. Hardaway, M. Erkan Ceyhan, N. Joseph Espat, Abdul Saied Calvino
Summary: This study evaluated colonoscopy utilization among Hispanic patients with a culturally tailored patient navigation program, showing an 85% completion rate of colonoscopy with no difference between males and females. Implementation of a CTPNP is an effective intervention to improve the CC rate and eliminate the historical gender gap in utilization among Hispanic patients.
Article
Neurosciences
Kaancan Deniz, Charlotte C. G. Ho, Kimberly G. Malphrus, Joseph S. Reddy, Thuy Nguyen, Troy P. Carnwath, Julia E. Crook, John A. Lucas, Neill R. Graff-Radford, Minerva M. Carrasquillo, Nilufer Ertekin-Taner
Summary: The study identified the effects of demographic and genetic variants on five potential plasma biomarkers in African Americans, including proteins related to AD pathology and inflammation. APOE genotype was associated with plasma A beta(42) and tau levels, with older age being correlated with higher levels.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Respiratory System
Esther Herrera-Luis, Angel C. Y. Mak, Javier Perez-Garcia, Elena Martin-Gonzalez, Celeste Eng, Kenneth B. Beckman, Scott Huntsman, Donglei Hu, Ruperto Gonzalez-Perez, Jose M. Hernandez-Perez, Elena Mederos-Luis, Yang Yie Sio, Paloma Poza-Guedes, Olaia Sardon, Paula Corcuera, Inmaculada Sanchez-Machin, Javier Korta-Murua, Carlos Martinez-Rivera, Joaquim Mullol, Xavier Munoz, Antonio Valero, Joaquin Sastre, Judith Garcia-Aymerich, Sabrina Llop, Maties Torrent, Maribel Casas, Jose R. Rodriguez-Santana, Jesus Villar, Victoria del Pozo, Fabian Lorenzo-Diaz, L. Keoki Williams, Erik Melen, Fook Tim Chew, Luisa N. Borrell, Esteban G. Burchard, Maria Pino-Yanes
Summary: This study used admixture mapping analyses and fine mapping to identify genetic variants associated with severe asthma exacerbations in Hispanic/Latino subgroups. The results showed limited transferability of these variants to other populations and their potential regulation of DPYSL3 and SCGB3A2 genes.
Article
Health Care Sciences & Services
Hector Morales, Moises Velasquez, Samira Negrete, Louise A. Kelly
Summary: The study reveals that there are differences in fundamental movement skills and physical fitness between Hispanic and Non-Hispanic White elementary school children. Hispanic children have lower fundamental movement skills and physical fitness compared to their Non-Hispanic White peers, which may have adverse implications for their physical fitness and health in adulthood.
Article
Genetics & Heredity
Charles Washington, Matthew Dapas, Arjun Biddanda, Kevin M. Magnaye, Ivy Aneas, Britney A. Helling, Brooke Szczesny, Meher Preethi Boorgula, Margaret A. Taub, Eimear Kenny, Rasika A. Mathias, Kathleen C. Barnes, Gurjit K. Khurana Hershey, Carolyn M. Kercsmar, Jessica D. Gereige, Melanie Makhija, Rebecca S. Gruchalla, Michelle A. Gill, Andrew H. Liu, Deepa Rastogi, William Busse, Peter J. Gergen, Cynthia M. Visness, Diane R. Gold, Tina Hartert, Christine C. Johnson, Robert F. Lemanske, Fernando D. Martinez, Rachel L. Miller, Dennis Ownby, Christine M. Seroogy, Anne L. Wright, Edward M. Zoratti, Leonard B. Bacharier, Meyer Kattan, George T. O'Connor, Robert A. Wood, Marcelo A. Nobrega, Matthew C. Altman, Daniel J. Jackson, James E. Gern, Christopher G. McKennan, Carole Ober
Summary: This study identified novel genetic variations at the 17q12-21 childhood-onset asthma locus that contribute to asthma severity in individuals with African ancestries, suggesting the presence of population-specific variants that contribute to genetic risk for asthma.
Article
Critical Care Medicine
Hongsheng Gui, Albert M. Levin, Donglei Hu, Patrick Sleiman, Shujie Xiao, Angel C. Y. Mak, Mao Yang, Andrea J. Barczak, Scott Huntsman, Celeste Eng, Samantha Hochstadt, Ellen Zhang, Kyle Whitehouse, Samantha Simons, Whitney Cabral, Sami Takriti, Goncalo Abecasis, Thomas W. Blackwell, Hyun Min Kang, Deborah A. Nickerson, Soren Germer, David E. Lanfear, Frank Gilliland, W. James Gauderman, Rajesh Kumar, David J. Erle, Fernando D. Martinez, Hakon Hakonarson, Esteban G. Burchard, L. Keoki Williams
Summary: This study identified a functional variant at the 17q12-21.1 locus associated with early-onset asthma in African American individuals. The lead signal, rs11078928, was found to be the top association for early-onset asthma after meta-analysis across cohorts. Additionally, a haplotype analysis suggested that the asthma association most closely with this variant.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Gerontology
Ann W. Nguyen, Harry Owen Taylor, Karen D. Lincoln, Fei Wang, Tyrone Hamler, Uchechi A. Mitchell
Summary: This study found that religious involvement is associated with sleep quality in older African Americans. Different types of religious involvement have different associations with sleep satisfaction and restless sleep.
JOURNAL OF AGING AND HEALTH
(2022)
Article
Substance Abuse
Yingning Wang, Wendy Max, Tingting Yao, Courtney Keeler, Hai-Yen Sung
Summary: The study examined the response of smoking behavior of African Americans and whites to tobacco prices, finding that daily smokers among African Americans are more affected by tobacco prices compared to whites, who are more influenced in terms of smoking intensity.
Article
Nursing
Veronica Barcelona, Ambre Flowers, Billy A. Caceres, Cindy A. Crusto, Jacquelyn Y. Taylor
Summary: This study investigated the associations between paternal co-residence and asthma, obesity, and blood pressure among children aged 3-5 years. While children who lived with their fathers were found to have a lower likelihood of asthma, this association became non-significant after adjusting for other factors. Paternal co-residence was not significantly associated with child obesity or blood pressure. Further research is needed to understand the impact of different family living situations on child health.
WESTERN JOURNAL OF NURSING RESEARCH
(2023)
Article
Oncology
Beth Savage, Peter D. Cole, Haiqun Lin, Charlotte Thomas-Hawkins
Summary: This study examined the relationship between race/ethnicity and pancreatitis in children hospitalized with acute lymphoblastic leukemia in the United States in 2016. Hispanic children were found to be at greater risk of pancreatitis compared to white children, while no significant differences were observed among black, Asian, or other-race children.
Article
Cardiac & Cardiovascular Systems
Josep Iglesies-Grau, Rodrigo Fernandez-Jimenez, Raquel Diaz-Munoz, Risa Jaslow, Amaya de Cos-Gandoy, Gloria Santos-Beneit, Christopher A. Hill, Alexandra Turco, Daniella Kadian-Dodov, Jason C. Kovacic, Zahi A. Fayad, Valentin Fuster
Summary: Non-Hispanic Black individuals are at greater risk of cardiovascular events compared to other racial/ethnic groups, and they appear to be more vulnerable to early subclinical atherosclerosis in young adults, even after adjusting for traditional cardiovascular risk factors and lifestyle factors.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Geriatrics & Gerontology
Robert Joseph Taylor, Antonius D. Skipper, James M. Ellis, Linda M. Chatters
Summary: This study examines church-based informal social support among older African Americans and Black Caribbeans. The findings indicate that church members are an important element of the social support networks for both groups. The study also emphasizes the importance of contact with church members for receiving emotional support.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Veronica Barcelona, Yunfeng Huang, Billy A. Caceres, Kevin P. Newhall, Qin Hui, Jessica P. Cerdena, Cindy A. Crusto, Yan Sun, Jacquelyn Y. Taylor
Summary: Potentially traumatic experiences may be related to chronic diseases, and epigenetic mechanisms could explain this association. The study found a significant association between DNAm at a CpG site in the ENOX1 gene and traumatic events in children.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)