Review
Medicine, General & Internal
Jessica Marinaro, Marc Goldstein
Summary: Male factor is significant in a couple's reproductive success, and advances in reproductive technology have overcome traditional barriers to male fertility. Collaborative work between reproductive endocrinologists and reproductive urologists is essential for optimizing fertility outcomes, improving men's health, and providing cost-effective care.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Aisha A. Abdulrazaq, Alessandra J. Ainsworth, Jeffrey W. Britton, Chandra C. Shenoy, Samir N. Babayev, Gregory D. Cascino, Kelsey M. Smith
Summary: The objective of this study was to determine seizure control in women with epilepsy undergoing assisted reproductive technology (ART). Retrospective chart review was conducted to identify WWE undergoing ART, and their demographics, epilepsy type, seizure control, and ART procedures were analyzed. The results showed no increased seizure frequency associated with fertility treatment and subsequent pregnancy in this small series of WWE.
Review
Medicine, General & Internal
Romualdo Sciorio, Claudio Manna, Patricia Fauque, Paolo Rinaudo
Summary: Since the birth of Louise Brown in 1978, over nine million children have been conceived using assisted reproductive technologies (ARTs). The potential epigenetic consequences of gametes and embryo manipulation during the preimplantation period have raised concerns. This review examines the evidence on oocytes and embryo cryopreservation and their potential impact on epigenetic regulation. Overall, the stress induced by vitrification procedures may lead to epigenetic and transcriptomic changes in oocytes and embryos, but it is unclear whether these changes will affect the health of future offspring.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Paversan Archary, Liezel Potgieter, Eman Elgindy, Rudolph Kantum Adageba, Justin Mboloko, Faye Iketubosin, Gamal Serour, Silke Dyer
Summary: This study investigates the utilization, practices, and outcomes of assisted reproductive technology (ART) in Africa in 2018 and 2019. The results show an increasing trend in the utilization of ART, with a high rate of multiple pregnancies, highlighting the need for improved follow-up of ART pregnancies.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Immunology
Xiangxin Lan, Ling Guo, Shiqin Zhu, Yongzhi Cao, Yue Niu, Shuwen Han, Zeyan Li, Yan Li, Junhao Yan
Summary: Pregnancy-induced hypertension (PIH) is a common pregnancy complication that affects the mother and fetus. The incidence of PIH is higher in pregnancies conceived after assisted reproductive technology (ART) than in spontaneous pregnancies. This study found that using a cytokine profile can effectively predict the risk of PIH in ART pregnancies, providing a basis for early intervention and prevention of PIH.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Endocrinology & Metabolism
Qian-Ling Li, Chao Wang, Ke-Xin Cao, Lin Zhang, Yun-Shuai Xu, Liang Chang, Zhen-Hui Liu, Ai-Jun Yang, Yan-Xue Xue
Summary: Sleep disorders are prevalent among infertile women undergoing assisted reproductive technology (ART) treatment. This study found that negative psychological factors, such as depression, anxiety, and perceived stress, were associated with poor sleep quality, while positive affect was linked to good sleep. Adverse sleep characteristics were found to decrease the quantity and quality of oocytes retrieved, fertilization rates, and clinical pregnancy rates. Screening and treatment for sleep disorders before ART treatment are crucial for optimizing treatment outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Georgina M. Chambers, Silke Dyer, Fernando Zegers-Hochschild, Jacques de Mouzon, Osamu Ishihara, Manish Banker, Ragaa Mansour, Markus S. Kupka, G. David Adamson
Summary: In 2014, 1.93 million ART cycles were performed in 76 countries, with trends showing increased success rates, frozen embryo transfer cycles, single embryo transfer, and preimplantation genetic testing. Utilization rates and effectiveness of ART continue to improve globally.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Manish Banker, Silke Dyer, Georgina M. Chambers, Osamu Ishihara, Markus Kupka, Jacques de Mouzon, Fernando Zegers-Hochschild, G. David Adamson
Summary: The report provides data on the utilization, effectiveness, and safety of assisted reproductive technology (ART) globally in 2013, showing an increase in ART cycles and changes in trends such as a rise in the proportion of older women undergoing non-donor ART. Further efforts are needed to improve the quality and consistency of reporting ART data by registries.
FERTILITY AND STERILITY
(2021)
Editorial Material
Oncology
Cock van Oosterhout, Daniel Marcu, Simone Immler
Summary: This article discusses the significant impact of genetic load on assisted reproductive technology, human reproduction, and fertility. It explores these topics in the context of evolutionary genetic theory, the technological revolution in ART, and the advancements in genomics and bioinformatics.
CLINICAL AND TRANSLATIONAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Mustapha Benkhalifa, Fabien Joao, Cynthia Duval, Debbie Montjean, Molka Bouricha, Rosalie Cabry, Marie-Claire Belanger, Hatem Bahri, Pierre Miron, Moncef Benkhalifa
Summary: After more than four decades of assisted reproductive technology (ART) practice, the failure of in vitro fertilization (IVF) treatments and recurrent implantation failures (RIFs) and repeated pregnancy loss (RPL) remain significant issues. This article reviews different therapeutic options and suggests that immunomodulation and predictive biomarkers may be promising solutions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, General & Internal
Laurianne Reitz, Vincent Balaya, Basile Pache, Anis Feki, Gregoire Le Conte, Achraf Benammar, Jean-Marc Ayoubi
Summary: This study aimed to evaluate the impact of unilateral salpingectomy on the number of mature follicles in the ipsilateral ovary during assisted reproductive technology (ART) cycles compared to the contralateral ovary. The study included 24 patients who underwent at least one ART cycle before and after unilateral salpingectomy. The results showed that the mean number of mature follicles was significantly reduced after salpingectomy in the operated side compared to the control side. This study suggests that salpingectomy may affect follicle recruitment on the ipsilateral side and highlights the importance of surgical indications and fertility preservation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Xiaoyan Lu, Yiying Sun, Meishan Han, Daoyuan Chen, Xiaoyan He, Siqi Wang, Kaoxiang Sun
Summary: We report silk fibroin-based microneedles for transdermal delivery of triptorelin-loaded nanoparticles to improve bioavailability and self-administration of triptorelin. The developed microneedles showed good mechanical properties and increased transdermal release of triptorelin, indicating their potential therapeutic role in assisted reproductive technology regimens.
Article
Obstetrics & Gynecology
Nicholas Saleem Raja, Colin B. Russell, Molly B. Moravek
Summary: This study discusses fertility concerns specific to LGBTQ+ and single-parent-to-be populations and reviews special considerations for evaluating and treating these patients in reproductive medicine. It emphasizes the need for equitable treatment regardless of sexual orientation or partner status and the importance of healthcare providers being comfortable and confident in addressing the needs of these populations.
FERTILITY AND STERILITY
(2022)
Article
Cell Biology
Brigita Vaigauskaite-Mazeikiene, Raminta Bausyte, Elvina Valatkaite, Ruta Mazelyte, Edita Kazenaite, Diana Ramasauskaite, Ruta Navakauskiene
Summary: In this study, the outcomes of ART in 223 couples with unexplained infertility were analyzed, and the gene expression associated with DNA modification, cell death, immune response, and senescence in infertile women's endometrium and follicular fluid were investigated. The results showed significant differences in women who successfully got pregnant compared to those unable to conceive, depending on age, duration of infertility, number of retrieved oocytes, zygotes, and transferred embryos. Furthermore, gene expression analysis revealed upregulation of genes associated with cell death and immune response in the endometrium of women who successfully got pregnant.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Obstetrics & Gynecology
Shu Qin Wei, Thuy Mai Luu, Marianne Bilodeau-Bertrand, Nathalie Auger
Summary: The study found that assisted reproductive technology (ART) is associated with an increased risk of hospitalization in children, particularly for infectious and allergic diseases. However, when controlling for genetic and environmental confounders, ART is not associated with an increased risk of childhood hospitalization.
FERTILITY AND STERILITY
(2022)
